Cutaneous manifestations in 1000 Pakistani newborns
Keywords:
Newborn, dermatoses, Mongolian spotsAbstract
Background Cutaneous manifestations are commonly seen in neonates. Benign dermatoses in newborns must be distinguished from more serious, life threatening disorders with cutaneous manifestations. Objective To determine the frequency of various dermatoses i.e. physiological and pathological among newborns up to 96 hours of age. Patients and methods 1000 full-term neonates were enrolled from labour rooms and pediatric nursery of Jinnah hospital, Lahore and were evaluated for cutaneous manifestations. All the relevant data regarding history, clinical examination and investigations were recorded and analyzed. Results Out of 1000 neonates, there were 469 boys and 531 girls. Their mean age was 72 hours (6-96 hrs). Cutaneous manifestations were present in 94% of babies and 82.5% babies had more than one manifestation. The most common dermatoses were Mongolian spots (63.2%), Epstein pearls (47.8%), sebaceous hyperplasia (44.8%), miliaria (12.8%), hypertrichosis (12%), erythema toxicum neonatorum (12%), salmon patch (12%) and impetigo (11.4%). Uncommon manifestations included desquamation 8.5%, omphalitis 8% and birth trauma (7.7%). Rare dermatoses were hemangiomas (3.5%), café-au-lait macules (2.6%), congenital melanocytic nevus (2.4%), acne neonatorum (0.9%), preauricular skin tag (0.4%), cutis marmorata telangiectatica congenita and collodion baby in (0.1%) each. Conclusion Cutaneous manifestations are frequent in newborns.ÂReferences
Pruksachatkunakorn C, Ana M, Durate, Lawrence A, Schachner H. Skin lesions in newborns. Int Pediatr 1999; 14: 28-31.
Kahana M, Feldman M, Abudi Z, Yurman S. Incidence of birth marks in Israeli neonates. Int J Dermatol 1995; 34: 704-6.
Frangu M, Gedde-Dahl T Jr, Verder H. Epidermolysis bullosa simplex Dowling-Meara. Ugeskr Laeger 2006; 168: 4222-4.
Muzaffar F, Hussain I. Pattern of skin diseases at Children Hospital, Lahore. J Pak Assoc Dermatol 2000; 10: 21-5.
Javed M, Jairamani C. Pediatric dermatology at Hamdard University Hospital, Karachi. J Pak Assoc Dermatol 2006; 16: 93-6.
Yasmeen N, Riaz M. Spectrum of common childhood skin diseases: single center experience. J Pak Med Assoc 2005; 55: 60-3.
Moosavi Z, Hooseini T. One-year survey of cutaneous lesions in 1000 consecutive Iranian newborns. Pediatr Dermatol 2006; 23: 61-3.
Nanda A, Kaur S, Bhakoo ON, Dhall K.. Survey of cutaneous lesions in Indian newborns. Pediatr Dermatol 1989; 6: 39-42.
Mc Kiernan JF, Spencer SA. Is sebaceous gland hyperplasia in newborn androgen induced? Early Hum Dev 1981; 55: 31-5.
Sonoda T, Itami S, Kurata S, Takayasu S. Influence of gonadal and adrenal androgens on the side glands of suncus mucinus. Endocrinol Jpn 1991; 38: 252-3.
Hidano A, Purwoko R, Jitsukawa K. Statistical survey of skin changes in Japanese neonates. Pediatr Dermatol 1986; 3: 140-4.
Thomson ML. A comparison between the number and distribution of functioning eccrine sweat glands in Europeans and Africans. J Physiol 1954; 123: 225-33.
Liu C, Feng J. Qu R et al. Epidemiologic study of predisposing factor in erythema toxicum neonatorum. Dermatology 2005; 210: 269-72.
Rivers JK, Frederiksen PC, Dibdin C. A prevalence survey of dermatoses in the Australian neonate. J Am Acad Dermatol 1990; 23: 77-81.
Saracli T, KenneyJA, Scott RB. Common skin disorders in newborn Negro infants. Observations based on examination of 1000 babies. J Pediatr 1963; 63: 358-62.
Chang MW, Jiang SB, Orlow SJ. Atypical erythema toxicum neonatorum of delayed onset in a term infant. Pediatr Dermatol 1999; 66: 137-41.
Kroon S, Clemmensen OJ, Hastrup N. Incidence of congenital melanocytic nevi in newborn babies in Denmark. J Am Acad Dermatol 1987; 17: 422-6.
