Efficacy of intralesional bleomycin versus cyotherapy in the treatment of palmoplanter warts
Keywords:
Palmoplantar warts, Intralesional bleomycin, CryotherapyAbstract
Objective To compare the efficacy of intralesional bleomycin versus cryotherapy in the treatment of palmoplantar warts. Methods A total of 70 patients having palmoplantar warts presenting to the department of Dermatology, Military Hospital Rawalpindi, from January 2019 onwards were included in the study. Approval from Hospital’s Ethical Committee was taken before commencement of the clinical trial. Patients having history of vascular diseases, Rynaurds, Systemic lupus erythematousous, chilblains, pregnant females, immunocompromized and comorbid conditions like diabetes mellitus and hypertension were excluded. Patients were allocated randomly by lottery method in to two groups. Group A patients were given intralesional bleomycin while Group B patients received cryotherapy. The response was then evaluated initially after 2 weeks and then after 2 months. A wart was considered clear if it completely resolves at the final evaluation (60 days after the initial procedure), otherwise, it was considered as treatment failure. Results The mean age of patients in group A was 31.60±11.52 years and in group B was 33.57±13.76 years. Out of 70 patients, 46 (65.71%) were males and 24 (34.31%) were females with male to female ratio of 1.9:1. Efficacy of Group A (intralesional bleomycin) was seen in 30 (85.71%) patients while in Group B (cryotherapy) it was seen in 19 (54.29%) patients. Conclusion This study concluded that intralesional bleomycin is better and efficacious than cryotherapy in treating palmoplantar warts.References
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