To assess the outcome of microneedling in the treatment of androgenetic alopecia
DOI:
https://doi.org/10.66344/jpad.34.4.2024.2711Keywords:
Androgenetic alopecia , Microneedling, Hamilton Norwood scaleAbstract
Objective To assess the outcome of microneedling in the treatment of androgenetic alopecia.  Methods A total of 90 cases meeting inclusion criteria were enrolled from dermatology OPD of Jinnah Hospital Lahore. After informed consent basic demographic details were obtained. Disease was classified according to the Hamilton Norwood scale and only patients with stage ||| and above were included. Microneedling was done with the help of dermapen R (Dr. Pen A7). The procedure was repeated after every 4 weeks (5 sessions) for six months. Final assessment was done one month after the last session.  Results Total of 90 patients, 51.1% (n=46) in the age group of 20-35 years and 48.9% (n=44) in the age group of 36-50 years. The mean age was 35.46±4.594 years. Distribution of duration of alopecia was 4.44±1.255 years. Disease staging of the patients showed that 6.7% (n=6) had Norwood Hamilton III, 28.9% (n=26) IV, 41.4% (n=37) V, and 23.3% (n=21) had VI stages of the disease. A total of 46 patients (51.1%) showed more than 50% improvement.  Conclusion In the current study, it was found that 51.1% (n=46) showed >50% improvement after 5 sessions of microneedling which were performed after every 4 weeks. ÂReferences
Kelly Y, Blanco A, Tosti A. Androgenetic alopecia: An update of treatment options. Drugs. 2016;76(14):1349-64.
Starace M, Alessandrini A, Brandi N, Piraccini BM. Preliminary results of the use of scalp microneedling in different types of alopecia. J Cosmetic Dermatol. 2020;19(3):646-50.
Salman KE, Altunay IK, Kucukunal NA, Cerman AA. Frequency, severity and related factors of androgenetic alopecia in dermatology outpatient clinic: hospital-based cross-sectional study in Turkey. An Bras Dermatol. 2017;92(1):35-40.
Lolli F, Pallotti F, Rossi A, Fortuna MC, Caro G, Lenzi A, et al. Androgenetic alopecia: a review. Endocrine. 2017;57(1):9-17.
Adil A, Godwin M. The effectiveness of treatments for androgenetic alopecia: A systematic review and meta-analysis. J Am Acad Dermatol. 2017;77(1):136-41.e5.
Dhurat R, Mathapati S. Response to Microneedling Treatment in Men with Androgenetic Alopecia Who Failed to Respond to Conventional Therapy. Indian J Dermatol. 2015;60(3):260-3.
Faghihi G, Nabavinejad S, Mokhtari F, Fatemi Naeini F, Iraji F. Microneedling in androgenetic alopecia; comparing two different depths of microneedles. J Cosmet Dermatol. 2020:1-7.
Bao L, Gong L, Guo M, Liu T, Shi A, Zong H, et al. Randomized trial of electrodynamic microneedle combined with 5% minoxidil topical solution for the treatment of Chinese male Androgenetic alopecia. J Cosmetic Laser Therapy. 2020;22(1):1-7.
Tosti A, Duque-Estrada B. Treatment strategies for alopecia. Expert Opin Pharmacother. 2009;10:1017-26.
Mella JM, Perret MC, Manzotti M, Catalano HN, Guyatt G. Efficacy and safety of finasteride therapy for androgenetic alopecia: A systematic review. Arch Dermatol. 2010;146:1141–50.
Jeong K, Lee YJ, Kim JE, Park YM, Kim BJ, Kang H. Repeated microneedle stimulation induce the enhanced expression of hair-growth-related genes. Int J Trichol. 2012;4:117.
Kim BJ, Lim YY, Kim HM, Lee YW, Won CH, Huh CH, et al. Hair follicle regeneration in mice after wounding by microneedle roller. Int J Trichol. 2012;4:117.
O’Toole EA, Mellerio JE. Wound healing. In: Burns TB, Cox N, Griffiths C, editors. Rook's Textbook of Dermatology. 8th ed. United Kingdom: Blackwell Publishing; 2010. pp. 14.1–27.
Puri N. A study on the efficacy of microneedling with minoxidil solution versus microneedling with hair multivitamin solution for the treatment of androgenetic alopecia. Int J Dermatol Clin Res. 2020;6(1):010-2.
Whiting DA. Possible mechanisms of miniaturization during androgenetic alopecia or pattern hair loss. J Am Acad Dermatol. 2001;45(3):S81-6.
Levy-Nissenbaum E, Bar-Natan M, Frydman M, Pras E. Confirmation of the association between male pattern baldness and the androgen receptor gene. Eur J Dermatol. 2005;15(5):339-40.
Tsuboi R, Tanaka T, Nishikawa T, Ueki R, Yamada H, Katsuoka K, Ogawa H, Takeda K. A randomized, placebo-controlled trial of 1% topical minoxidil solution in the treatment of androgenetic alopecia in Japanese women. Eur J Dermatol. 2007;17(1):37-44.
Dhurat R, Sukesh M, Avhad G, Dandale A, Pal A, Pund P. A randomized evaluator blinded study of effect of microneedling in androgenetic alopecia: a pilot study. Int J Trichol. 2013;60(3):260.
Lewis W. Is Microneedling Really the Next Big Thing?. Practice. 2014 Jul.
Jeong K, Lee YJ, Kim JE, Park YM, Kim BJ, Kang H. Repeated microneedle stimulation induce the enhanced expression of hair-growth-related genes. Int J Trichol. 2012;4:117.
Kim BJ, Lim YY, Kim HM, Lee YW, Won CH, Huh CH, et al. Hair follicle regeneration in mice after wounding by microneedle roller. Int J Trichol. 2012;4:117.
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