Assessment of clinical efficacy of Q-switched Nd:YAG laser 1064-nm in onychomycosis
Keywords:
Onychomycosis, 1064-nm Nd:YAG wavelength laser, Systemic antifungal agentsAbstract
Objective Onychomycosis (OM) is a chronic fungal infection of the finger and toenails. Emerging treatments include lasers, like CO2 laser and Nd:YAG Laser 1064-nm which combine both efficacy and safety. The objective of the study is to determine the clinical efficacy of Q-switched Nd:YAG Laser 1064-nm in OM. Methods This study undertaken in Dermatology Department, Mayo Hospital, Lahore was conducted on 118 adult patients with clinical OM and positive KOH smear for fungal hyphae. Results There was mild female predominance (54% females versus 46% males) in the subjects. More than one third (35.6%) of the subjects had an excellent clinical response and only 5.1% had a poor response. Disease duration longer than 6 months was significantly associated with poorer outcome. No side effects were observed except mild discomfort during the treatment session. Conclusion Q-Switched Nd:YAG Laser 1064-nm is an effective noninvasive treatment option for OM in our population. It should be considered in all patients with recent disease onset, especially where long term systemic agents are contraindicated or poorly tolerated.References
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