Histomorphology of lichenoid tissue reactions: A retrospective study
Keywords:
Histopathology, Lichenoid tissue reaction, lichen planusAbstract
Objective To analyse variety of disorders comprising of lichenoid tissue reactions on the basis of their respective histomorphological features. Â Methods A 2-year retrospective study was conducted on skin biopsies with presence of lichenoid tissue reactions. On histopathological examination, lichenoid reactions were identified in a total of 184 cases, out of which 147 were lichen planus and 37 showed lichenoid eruptions. Â Results Out of the total of 184 cases, females (62.5%) were more commonly affected. Most common site of predilection being extremities (34.23%). Among the lichenoid tissue reactions, lichen planus (29.89%) and lichen planus pigmentosus (23.36%) constituted majority of cases. Presence of band-like lymphocytic infiltrate is the most constant histopathological finding of lichenoid tissue reaction followed by basal cell layer vacuolization, hyperkeratosis, hypergranulosis, acanthosis, and pigment incontinence. Â Conclusion Thus, histopathology is an essential tool for reaching to a conclusive diagnosis, amongst the vast list of differential diagnosis of lichenoid tissue reactions with similar clinical presentation. ÂReferences
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