Comparison of efficacy of Eflornithine and Nd:YAG laser in combination therapy versus Nd:YAG laser alone for treatment of idiopathic facial hirsutism

Nd yag and eflornithine combination in hirsutism

Authors

  • Saadiya Siddiqui Department of Dermatology, Ammerudin Medical College/ Post Graduate Medical Institute, Lahore
  • Nauman Bashir Azam Services Institute of Medical Sciences/ Services Hospital, Lahore
  • Muhammad Anees
  • saba nasim
  • Shahbaz Aman Department of Dermatology, Ammerudin Medical College/ Post Graduate Medical Institute, Lahore.

Keywords:

Hirsutism, Eflornithine, Nd:YAG laser, Lasers hair removal, Aesthetic dermatology

Abstract

Objective To compare the efficacy of Eflornithine and Nd:YAG laser in combination therapy versus Nd:YAG laser alone in treating patients of idiopathic facial hirsutism.   Methods This randomized controlled trial was done from 9th April 2019 to 8th December 2019 in Dermatology department, Services Hospital, Lahore. Total 80 female with idiopathic hirsutism, 18-45 years of age, randomized into two groups. Group A was treated with combination therapy of Eflornithine and Nd:YAG laser and Group B was given Nd:YAG laser alone. The patients were followed at 4 weeks interval till 24 weeks to observe efficacy. Final assessment was done on 8th visit (taking baseline at 0 and 24th week as final session). Hair counts were done in 1 cm2 surface area of the treated area.   Results Both groups A and B had 40 patients each, from 18-45 years with mean age of 29.05±5.89 years. The mean ages of patients in group A and B was 29.10±6.03 and 29.03±5.82 years respectively. Majority of the patients 52 (65.0%) were between 18 to 30 years of age. Efficacy of Group A (Eflornithine and Nd:YAG laser) was seen in 37 (92.50%) patients while in Group B (Nd:YAG laser alone) was seen in 29 (72.50%) patients (p-value = 0.018).   Conclusion This study concluded that combination of eflornithine and Nd:YAG laser is more efficacious than that of Nd:YAG laser alone in treatment of idiopathic hirsutism.  

Author Biographies

Saadiya Siddiqui, Department of Dermatology, Ammerudin Medical College/ Post Graduate Medical Institute, Lahore

Assistant Professor Dermatology Ammerudin medical college /post graduate medical institute lhr

Nauman Bashir Azam, Services Institute of Medical Sciences/ Services Hospital, Lahore

resident dermatologist

Muhammad Anees

resident dermatologist

saba nasim

resident dermatologist

Shahbaz Aman, Department of Dermatology, Ammerudin Medical College/ Post Graduate Medical Institute, Lahore.

professor dermatology

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Published

2024-05-06

How to Cite

1.
Siddiqui S, Azam NB, Anees M, nasim saba, Aman S. Comparison of efficacy of Eflornithine and Nd:YAG laser in combination therapy versus Nd:YAG laser alone for treatment of idiopathic facial hirsutism: Nd yag and eflornithine combination in hirsutism. J Pak Assoc Dermatol [Internet]. 2024May6 [cited 2024May22];34(1):40-5. Available from: https://jpad.com.pk/index.php/jpad/article/view/2658

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