The comparison of dyslipidemia in patients with and without acne vulgaris
Keywords:Acne vulgaris, Serum lipid levels, Dyslipidemia
AbstractObjective Acne vulgaris (AV) is the most common skin disease worldwide. It affects pilosebaceous unit and leads to range of lesions. In acne patients the serum lipid levels are altered as compared to individuals without acne. The main objective of the study is to determine the association between dyslipidemia and acne vulgaris. Methods This case control study was done in Dermatology Department, Mayo Hospital, Lahore between 16-10-2020 to 15-04-2021. Total 246 cases (123 acne patients and 123 controls) were enrolled by non-probability, consecutive sampling. Results Among 123 cases; mean total cholesterol was 188.4±26.2 mg/dl in cases. Mean of TG was 189.8211±59.42884 (minimum was 119 and maximum was 305). Mean of LDL 153.3984±28.77007 (minimum was 120 and maximum was 290). Mean of HDL was 33.9106±8.24821 (minimum was 20 and maximum was 43). Among 123 controls; Mean Total cholesterol was 212.8±58.3 mg/dl in controls. Mean of TG was 163.4472±69.88916 (minimum was 109 and maximum was 352). Mean of LDL 137.3659±19.92620 ((minimum was 105 and maximum was 170). Mean of HDL was 40.4228±7.86047 (minimum was 29 and maximum was 50). Odds of having dylipidemia among cases were 1.9. Conclusion BMI, LDL-C and Triglycerides were raised significantly in acne patients as compared to controls while HDL-C was markedly low in cases. Dyslipidemia found significant among cases as compared to controls. Acne patients of younger age, female gender and normal BMI were more likely to have dyslipidemia.
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