A comparison of treatment efficacy of chemical reconstruction of skin scars using 50% trichloroacetic acid peel with microneedling in acne scars

Authors

  • Aiman Asif Department of Dermatology, Services Hospital/ Services Institute of Medical Sciences, Lahore
  • Saelah Batool Department of Dermatology, Services Hospital/ Services Institute of Medical Sciences, Lahore.
  • Hira Tariq Dermatology
  • Iqra Mariam Department of Dermatology, Services Hospital/ Services Institute of Medical Sciences, Lahore.
  • Tehreem Aslam Department of Dermatology, Services Hospital/ Services Institute of Medical Sciences, Lahore.
  • Faria Asad Department of Dermatology, Services Hospital/ Services Institute of Medical Sciences, Lahore.
  • Shahbaz Aman Department of Dermatology, Services Hospital/ Services Institute of Medical Sciences, Lahore

Keywords:

Acne scars, 50% trichloroacetic acid peel, Microneedling, Efficacy

Abstract

Objective To assess the effectiveness of chemical reconstruction of skin scars (CROSS) using 50% TCA peel and Microneedling in acne scars.   Methods This trial was carried out from 15th March to 14th September 2022, at Outpatient Department of Dermatology, Services Hospital, Lahore. Patients of both genders and 18 to 50 years of age, who had grade 2 to 4 acne scars were enrolled. Their acne scars were graded by Goodman’s Qualitative Acne Scarring Grading System. Paper lottery method was used to randomly divide them into 2 groups. Group A patients received 50% TCA peel whereas in Group B, patients were treated with microneedling with dermapen. Follow-up was done one month after the last treatment session and the response was recorded. Excellent response was labelled if patient’s acne scars reduced by two grades, good response if one grade was reduced and a poor response was no improvement. Efficacy was considered as good or excellent response.   Results A total of 84 patients were enrolled. The mean of the ages of patients in group A was 33.21±7.22 years and in group B was 32.12±6.59 years. Majority of the patients 60 (71.43%) were between 18 to 35 years of age. Out of 84 patients, 73 (86.90%) were females and 11 (13.10%) were males with female to male ratio of 6.6:1. Efficacy of Group A (50% TCA peel) was noted in 31 (73.81%) patients while in Group B (microneedling with dermapen) it was seen in 39 (92.86%) patients (p-value = 0.019).   Conclusion We concluded that microneedling with dermapen was more efficacious in the treatment of post acne facial scars than chemical reconstruction of scars (CROSS) with 50% TCA peel.  

References

Babar O, Mobeen A. Prevalence and Psychological Impact of Acne Vulgaris in Female Undergraduate Medical Students of Rawalpindi and Islamabad. Pakistan. Cureus. 2019;11(9):e5722.

DOI 10.7759/cureus.5722

Fife D. Evaluation of Acne Scars. How to Assess Them and What to Tell the Patient. Dermatol Clin [Internet]. 2016:34(2):207-13.

Available from: http://dx.doi.org/10.1016/j.det.2015.11.009

Deirdre Connolly, Ha Linh VU. Kavita Mariwalla NS. Acne Scarring- pathogenesis, evaluation, and treatment options. J Clin Aesthet Dermatol. 2017:10(9):12-23.

Cachafeiro T, Escobar G, Maldonado G. Cestari T, Corleta 0. Comparison of nonablative fractional erbium laser 1,340 nm and microneedling for the treatment of atrophic acne scars: A randomized clinical trial. Dermatologic Sui.2016:42(2):13-41.

Damasceno PS, Maria 1, Costa C, Gabrielle K. Gomes P. Chemical and Physical Peelings. Chemical Physical Peelings. 2016;98(2):121-4.

Ramaut L, Hoeksema H, Pirayesh A, Stillaert F. Monstrey S. Microneedling: Where do we stand now? A systematic review of the literature. J Plast Reconstr Aesthetic Surg [Internet].2018;71(1):1-14.

Anum S. Outcome of microneedling combined wtih 35% focal trichlorooacetic acid peeling in post ache atrophic scars. J Pak Assoc Dermatol. 2020:30(2):242-8.

Ehsan I, Ahsan U, Sultan N. Comparison of efficacy of 50% TCA using CROSS technique with microneedling for the treatment of atrophic acne scars. JSMDC Pak. 2020;16(01):26-31.

Goodman GJ, Baron JA. Postacne scarring–a quantitative global scarring grading system. J Cosmet Dermatol.2006;5:48-52.

Chilicka K, Rusztowicz M, Szyguła R, Nowicka D. Methods for the Improvement of Acne Scars Used in Dermatology and Cosmetology: A Review. J Clin Med. 2022; 11(10):2744.

Dhollan N, Thirunavukkarasu V. Microneedling vs. chemical reconstructon of skin scars with trichloroacetic acid: a comparative study. Int J Res Dermatol. 2017;3:277-81.

Agarwal N, Gupta LK, Khare AK, Kuldeep CM, Mittal A. Therapeutic Response of 70% Trichloroacetic Acid CROSS in Atrophic Acne Scars. Dermato Surg. 2015;41:597–604.

Bhardwaj D, Khunger N. An Assessment of the Efficacy and Safety of CROSS Technique with 100% TCA in the Management of Ice Pick Acne Scars. J Cutan Aesthet Surg. 2010;3:93–6.

Al-Hamamy HR, Al-Dhalimi MA, Abtan AF. Evaluation of treatment of acne scars with 25% trichloroacetic acid chemical peel followed by manual dermasanding. J Cosmet Dermatol 2021;20:1750–5.

Tirmizi SS, Iqbal T, Mansoor M, Farooq N, Ather S, Fatima F, Kapadia N, Anwar A, Hashmi AA. Role of Microneedling in Atrophic Post-Acne Scars: An Experience from a Tertiary Care Hospital. Cureus. 2021;13:e12578.

Biesman BS, Cohen JL, Dibernardo BE, Emer JJ, Geronemus RG, Gold MH, Lehman AS, Pilcher BK, Monheit GD, Schlesinger TE, et al. Treatment of Atrophic Facial Acne Scars with Microneedling Followed by Polymethylmethacrylate-Collagen Gel Dermal Filler. Dermatol Surg. 2019;45:1570–9.

Schoenberg E, O’Connor M, Wang JV, Yang S, Saedi N. Microneedling and PRP for acne scars: A new tool in our arsenal. J Cosmet Dermatol. 2020;19:112–4.

Published

2024-05-06

How to Cite

1.
Asif A, Batool S, Hira Tariq, Mariam I, Aslam T, Asad F, Aman S. A comparison of treatment efficacy of chemical reconstruction of skin scars using 50% trichloroacetic acid peel with microneedling in acne scars. J Pak Assoc Dermatol [Internet]. 2024May6 [cited 2025Mar.17];34(1):159-64. Available from: https://jpad.com.pk/index.php/jpad/article/view/2598

Issue

Section

Original Articles

Similar Articles

You may also start an advanced similarity search for this article.

Most read articles by the same author(s)

1 2 3 4 5 6 7 8 9 10 > >>