Comparison of efficacy of 10% potassium hydroxide (KOH) versus liquid nitrogen cryotherapy in the treatment of palmoplantar warts

Authors

  • Fatima Bashir AMC /PGMI/ Lahore General Hospital, Lahore
  • Kehkshan Tahir Fatima Jinnah Medical University/ Sir Ganga Ram Hospital, Lahore
  • Ghazia Shaheen AMC/PGMI/ Lahore General Hospital, Lahore
  • Anum Naveed AMC/ PGMI/ Lahore General Hospital, Lahore
  • Ayesha Shafqat AMC/ PGMI/ Lahore General Hospital, Lahore
  • Maria Azad AMC/ PGMI/ Lahore General Hospital, Lahore

Keywords:

Cryotherapy, Human Papilloma Virus (HPV), Potassium hydroxide (KOH), Warts

Abstract

Background Viral Warts are benign epidermal proliferations caused by Human Papilloma Virus (HPV). Different types of cutaneous warts include flat warts, palmoplantar warts, common warts, genital warts etc. Treatment options includes salicylic acid, formaldehyde, liquid nitrogen cryotherapy, trichloroacetic acid (TCA), tretinoin, potassium hydroxide (KOH) and cauterization. Objective To compare the efficacy of 10% KOH solution versus liquid nitrogen (cryotherapy) in the treatment of palmoplantar warts. Method  A total of 120 patients of palmoplantar warts fulfilling inclusion and exclusion criteria were inducted in the study. Patients were randomly divided into two groups; 60 patients in Group A received 10% KOH solution daily at night while 60 patients in Group B were treated with liquid nitrogen cryotherapy weekly by cotton bud method. Efficacy was assessed at the end of 4 weeks for both groups. Treatment was labelled as efficacious if complete disappearance of warts occurred after 4 weeks of therapy. Results  Mean age of patients was 22.97 + 10.69 years. Efficacy was seen in 73.3% of patients in group A and 60% of patients in group B. Treatment was found to be efficacious in both groups and there was no statistically significant difference in efficacy between these treatment modalities. Conclusion  10% KOH was found to be equally effective as liquid nitrogen cryotherapy in treating palmoplantar warts. Key words Cryotherapy, Human Papilloma Virus (HPV), Potassium hydroxide (KOH), Warts.  

Author Biographies

Fatima Bashir, AMC /PGMI/ Lahore General Hospital, Lahore

Department of Dermatology

Kehkshan Tahir, Fatima Jinnah Medical University/ Sir Ganga Ram Hospital, Lahore

Department of Dermatology Associate Professor

Ghazia Shaheen, AMC/PGMI/ Lahore General Hospital, Lahore

Department of Dermatology

Anum Naveed, AMC/ PGMI/ Lahore General Hospital, Lahore

Department of Dermatology

Ayesha Shafqat, AMC/ PGMI/ Lahore General Hospital, Lahore

Department of Dermatology

Maria Azad, AMC/ PGMI/ Lahore General Hospital, Lahore

Department of Dermatology  

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Published

2024-05-06

How to Cite

1.
Fatima Bashir, Kehkshan Tahir, Ghazia Shaheen, Anum Naveed, Ayesha Shafqat, Maria Azad. Comparison of efficacy of 10% potassium hydroxide (KOH) versus liquid nitrogen cryotherapy in the treatment of palmoplantar warts. J Pak Assoc Dermatol [Internet]. 2024May6 [cited 2024May19];34(1):185-90. Available from: https://jpad.com.pk/index.php/jpad/article/view/2551

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