A rare association of Sweet syndrome in a diagnosed case of pemphigus vulgaris
Keywords:
Sweet Syndrome, Pemphigus vulgaris., Neutrophilic dermatosisAbstract
Sweet syndrome (SS) is a rare neutrophilic dermatosis. It is characterized by acute onset of fever and painful erythematous papules, plaques and nodule on skin. SS may affect other organs. Pemphigus Vulgaris is an immune mediated condition which is characterized by the flaccid blisters affecting mainly trunk and mucosae with painful erosions. A 59 years old male, diagnosed case of Diabetes Mellitus and Pemphigus vulgaris, presented to our outpatient department with fever and multiple painful erythematous plaques, nodules and ulcers on both lower limbs. He was in remission phase of pemphigus vulgaris with immunosuppressants namely steroids and azathioprine. Patient fulfilled diagnostic criteria of Sweet syndrome. During his stay in the department of dermatology, he developed neurological manifestations in the form of weakness of the left proximal upper limb with altered sensorium. Cerebrovascular infarct was confirmed on computed tomography (CT) scan. Cerebrovascular infarct is a very rare manifestation of neuro-Sweet disease. SS is associated with many conditions. It is reported in various autoimmune conditions. But as far as pemphigus vulgaris is concerned SS is reported very rarely with pemphigus vulgarisReferences
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