Serum zinc levels and their impact on quality of life of patients with atopic dermatitis


  • Thuy Nguyen Dac Luong University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam
  • Thi Thuy Trang Vu Tam Anh Hospital, Ho Chi Minh City, Vietnam
  • Thi Phuong Thao Doan District 11 Hospital, Ho Chi Minh city, Vietnam
  • Quoc Dung Pham District 11 Hospital, Ho Chi Minh city, Vietnam


Atopic dermatitis, DLQI, pruritus, quality of life, serum zinc levels


Background: Atopic dermatitis is a chronic, recurrent disease characterized by pruritus and eczematous lesions. Several studies have shown that atopic dermatitis severely affects the quality of life and atopic dermatitis patients have low serum zinc levels. Objectives: This study aimed to evaluate the impact of atopic dermatitis on the quality of life and quantify the relationship between serum zinc levels and patients’ well-being. Materials and Methods: A cross-sectional study was conducted. Atopic dermatitis was diagnosed according to the Hanifin and Rajka criteria of 1980, and the severity was assessed using the Scoring Atopic Dermatitis (SCORAD) scale. The Dermatology Life Quality Index (DLQI) was used to evaluate the quality of life in patients. The itch severity was measured using the 5-D itch scale. Results: A total of 87 patients and 87 healthy individuals were enrolled in the study. The “itching” component had the highest DLQI score. A statistical correlation was observed between the SCORAD score and the DLQI score. In the patient group, the serum zinc levels were lower than that in the control group. Additionally, there was a negative correlation between the SCORAD scores, the DLQI scores, and the 5-D scores against serum zinc levels. Conclusions: Atopic dermatitis is associated with low serum zinc levels; both have a major impact on patients’ quality of life.


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How to Cite

Luong TND, Vu TTT, Doan TPT, Pham QD. Serum zinc levels and their impact on quality of life of patients with atopic dermatitis . J Pak Assoc Dermatol [Internet]. 2024Apr.21 [cited 2024May22];34(2):500-5. Available from:



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