Skin infection treatment by using spilanthes acmella methanolic extract emulgel

Spilanthes acmella Methanolic and its Clinical Efficacy in Skin Infections

Authors

  • Aqsa Afzal Department of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan
  • Nisar Hussain Shah Department of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan
  • Irshad Hussain Institute of Pharmacy, Shaheed Mohtarma Benazir Bhutto Medical University, Larkana, Pakistan
  • Naveed Nisar Department of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan
  • Romana Riaz Department of Pharmaceutics, Bakhtawar Ameen College of Pharmaceutical Sciences, Multan, Pakistan
  • Amina Riaz Department of Pharmacy, The Women University Multan, Pakistan. and School of Pharmacy, University College London, United Kingdom.
  • Javaria Saeed Department of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan

Keywords:

Eczema, Skin dermatitis, Skin infections, Spilanthes acmella, Plant extract, Herbal remedies

Abstract

Background Skin infections can range in severity from moderate to severe. However, skin infections can become more serious if they penetrate deeper into the skin or spread across a large portion of the body. Most skin infections are caused by specific bacteria, fungi, allergens, or other factors.   Objective To examine the efficacy of an emulgel made from Spilanthes acmella extract as a herbal treatment for treating cellulitis and bacterial skin eruption.   Methods From May to June 2021, this randomized controlled trial was carried out at a neighborhood clinic in Multan. Three patients took part in the study, and each one received an emulgel based on Spilanthes acmella that contained 2% pure extract. For a total of 14 days, each patient applied emulgel three times each day to the suffering area. Each patient had pictures taken on the 0th, 7th, and 14th days.   Results All patients' skin infections had greatly improved after 14 days, as seen in the post-14-days figures. The eczematous conditions got better, the skin softer, and every one of the lesions and skin eruptions had cleared out.   Conclusion It has been determined that the S extract base emulgel demonstrated a strong anti-inflammatory, anti-fungal, and anti-bacterial activity to treat many kinds of infectious and eczematous skin disorders. Due to the formulation's emollient effect, which lasted between 7 and 14 days, the skin became normal and smooth.  

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Published

2024-05-06

How to Cite

1.
Afzal A, Shah NH, Hussain I, Nisar N, Riaz R, Riaz A, Saeed J. Skin infection treatment by using spilanthes acmella methanolic extract emulgel: Spilanthes acmella Methanolic and its Clinical Efficacy in Skin Infections . J Pak Assoc Dermatol [Internet]. 2024May6 [cited 2025Jan.20];34(1):130-3. Available from: https://jpad.com.pk/index.php/jpad/article/view/2473

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