Comparison of outcome of microneedling with autologus platelet rich plasma verses microneedling with topical insulin in the treatment of post-acne atrophic scars
Keywords:Acne vulgaris, Micro-needling, Platelet Rich Plasma, Insulin, Post-acne atrophic scar
AbstractBACKGROUND: Treatment of acne scars involves a concoction of various treatment modalities. Minimally invasive procedures like micro-needling along with platelet rich plasma are new combination modalities used for scar remodeling with lesser downtime and side effects. The aim of this study was to compare the outcome of micro-needling with PRP versus micro-needling with topical insulin in post-acne atrophic scars, as topical insulin is natural component of body, cheap, easy to use, minimally invasive and a new therapy for post-acne scars that showed good results in the studies mentioned. No local study was found in literature research. Hence, any effect of this potentially very effective therapeutic modality needs to be investigated. OBJECTIVE: To compare the outcome of micro-needling with autologous platelet rich plasma versus micro-needling with topical insulin in the treatment of post-acne atrophic scars RESULTS: In group-A, 10(25.0%) were males and 30(75.0%) were females, while in group-B, 13(32.5%) were males and 27(67.5%) were females. The mean age of patients in group-A was 23.68±5.03 years and 24.48±4.75 years in group-B. The mean duration of scar in group-A was 4.5±2.1 years and 4.9±2.3 years in group-B. The mean exposure to sunlight in group-A was 4.9±2.3hours and 4.7±2.1hours in group-B. The mean percentage reduction in grades of scar in group-A was 55.42±12.74% and 23.33±16.79% in group-B. CONCLUSION: Micro-needling along with insulin appears to be a better therapeutic modality than micro-needling with PRP for the treatment of acne scars. This combination procedure does not require expensive equipment and could be done in all skin type patients as post-inflammatory hyperpigmentation is rarely seen after the therapy. Also this novel combination procedure is convenient for both doctors and patients as no high skills are required, no need to take I/V line and less time consuming.
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