Effect of Skinny Drip Method on Body Mass Index and Physical Appearance of Obese Population


  • Uzma Dost Muhammad Rajar Department of Dermatology, Isra University Hyderabad
  • Asher Ahmed Mashhood Department of Dermatology, Combined Military Hospital, Rawalpindi
  • Attiya Tareen Department of Dermatology, Foundation University Medical College Rawalpindi


Obesity, Body Mass Index, Lipid metabolism


Introduction The purpose of this study is to determine the effects of slim drip approach by mixing cartinex 1g/5ml, Liponex 300gm/12ml and Arginex 5g/10ml with a 500ml of normal saline being administered to patients for twice a week and to determine its effects on Body Mass Index and Physical appearance of patients after one month of intervention. Methodology A total number of n=400 participants were recruited. Informed consent was taken prior to induction and initial body mass index in kg/m2 was monitored Results The findings of this study had revealed that slimming drip had significantly p<0.005 reduced the body mass index of the participants where the mean values of BMI before the start of treatment were 38.12±4.85kg/m2 that had been reduced to 34.49±5.36 after one month of treatment. Conclusion The study had concluded that skinny drip treatment had produced a beneficial effect on hormonal levels and patient’s appearance.


Jepsen S, Suvan J, Deschner J. The association of periodontal diseases with metabolic syndrome and obesity. Periodontology 2000. 2020 Jun;83(1):125-53.

Muscogiuri G, Verde L, Sulu C, Katsiki N, Hassapidou M, Frias-Toral E, Cucalón G, Pazderska A, Yumuk VD, Colao A, Barrea L. Mediterranean Diet and Obesity-related Disorders: What is the Evidence?. Current Obesity Reports. 2022 Sep 30:1-8.

Chooi YC, Ding C, Magkos F. The epidemiology of obesity. Metabolism. 2019 Mar 1;92:6-10.

Rippe JM. Adiposity-Based Chronic Disease: A New Diagnostic Term. InObesity Prevention and Treatment 2021 Sep 23 (pp. 123-131). CRC Press.

Mechanick JI. Adiposity-based chronic disease—obesity re-worked. US Endocrinol. 2016;12:102.

Upadhyay J, Farr O, Perakakis N, Ghaly W, Mantzoros C. Obesity as a disease. Medical Clinics. 2018 Jan 1;102(1):13-33.

Cawley J, Meyerhoefer C, Biener A, Hammer M, Wintfeld N. Savings in medical expenditures associated with reductions in body mass index among US adults with obesity, by diabetes status. Pharmacoeconomics. 2015 Jul;33(7):707-22.

Peirson L, Fitzpatrick-Lewis D, Morrison K, Ciliska D, Kenny M, Ali MU, Raina P. Prevention of overweight and obesity in children and youth: a systematic review and meta-analysis. Canadian Medical Association Open Access Journal. 2015 Jan 13;3(1):E23-33.

American College of Cardiology, American Heart Association Task Force on Practice Guidelines. Guidelines (2013) for managing overweight and obesity in adults. Preface to the Expert Panel Report. Obesity (Silver Spring, Md). 2014;22(Suppl 2):S40.

Semlitsch T, Stigler FL, Jeitler K, Horvath K, Siebenhofer A. Management of overweight and obesity in primary care—A systematic overview of international evidence‐based guidelines. Obesity Reviews. 2019 Sep;20(9):1218-30.

Wadden TA, Tronieri JS, Butryn ML. Lifestyle modification approaches for the treatment of obesity in adults. American psychologist. 2020 Feb;75(2):235.

Gillen JB, Gibala MJ. Interval training: a time-efficient exercise strategy to improve cardiometabolic health. Applied Physiology, Nutrition, and Metabolism. 2018;43(10):iii-v.

Keating SE, Johnson NA, Mielke GI, Coombes JS. A systematic review and meta‐analysis of interval training versus moderate‐intensity continuous training on body adiposity. Obesity reviews. 2017 Aug;18(8):943-64.

Forgione N, Deed G, Kilov G, Rigas G. Managing obesity in primary care: breaking down the barriers. Advances in therapy. 2018 Feb;35(2):191-8.

Dani V, Yao X, Dani C. Transplantation of fat tissues and iPSC-derived energy expenditure adipocytes to counteract obesity-driven metabolic disorders: Current strategies and future perspectives. Reviews in Endocrine and Metabolic Disorders. 2022 Feb;23(1):103-10.

Stoner L, Beets MW, Brazendale K, Moore JB, Weaver RG. Exercise dose and weight loss in adolescents with overweight–obesity: a meta-regression. Sports Medicine. 2019 Jan;49(1):83-94.

Friedenreich CM, Ruan Y, Duha A, Courneya KS. Exercise dose effects on body fat 12 months after an exercise intervention: follow-up from a randomized controlled trial. Journal of obesity. 2019 Jan 20;2019.

Idrees Z, Cancarevic I, Huang L. FDA-approved pharmacotherapy for weight loss over the last decade. Cureus. 2022 Sep 17;14(9).

Kushner RF. Weight loss strategies for treatment of obesity: lifestyle management and pharmacotherapy. Progress in cardiovascular diseases. 2018 Jul 1;61(2):246-52.

Zhang T, Zhang L, Ke B, Sun J, Liu T, Huang Y, Chen X, Liu M, Li F, Luo D, Qin J. L-carnitine ameliorated weight loss in fasting therapy: a propensity score-matched study. Complementary Therapies in Medicine. 2019 Jun 1;44:162-5.

Pooyandjoo M, Nouhi M, Shab‐Bidar S, Djafarian K, Olyaeemanesh A. The effect of (L‐) carnitine on weight loss in adults: a systematic review and meta‐analysis of randomized controlled trials. Obesity reviews. 2016 Oct;17(10):970-6.

Kucukgoncu S, Zhou E, Lucas KB, Tek C. Alpha‐lipoic acid (ALA) as a supplementation for weight loss: results from a meta‐analysis of randomized controlled trials. Obesity reviews. 2017 May;18(5):594-601.

Koh EH, Lee WJ, Lee SA, Kim EH, Cho EH, Jeong E, Kim DW, Kim MS, Park JY, Park KG, Lee HJ. Effects of alpha-lipoic acid on body weight in obese subjects. The American journal of medicine. 2011 Jan 1;124(1):85-e1.

Xu C, Wang X, Han F, Qi C, Li E, Guo J, Qin JG, Chen L. α-lipoic acid regulate growth, antioxidant status and lipid metabolism of Chinese mitten crab Eriocheir sinensis: Optimum supplement level and metabonomics response. Aquaculture. 2019 May 15;506:94-103.

Genazzani AD, Prati A, Genazzani AR, Battipaglia C, Simoncini T, Szeliga A, Podfigurna A, Meczekalski B. Synergistic effects of the integrative administration of acetyl-L-carnitine, L-carnitine, L-arginine and N-acetyl-cysteine on metabolic dynamics and on hepatic insulin extraction in overweight/obese patients with PCOS. Gynecol. Reprod. Endocrinol. Metab. 2020;1:56-63.




How to Cite

Rajar UDM, Mashhood AA, Tareen A. Effect of Skinny Drip Method on Body Mass Index and Physical Appearance of Obese Population. J Pak Assoc Dermatol [Internet]. 2023Oct.12 [cited 2023Nov.28];33(4):1436-41. Available from: https://jpad.com.pk/index.php/jpad/article/view/2369



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