Frequency of anti-HCV antibodies in lichen planus patients attending a tertiary care hospital Quetta, Balochistan

Authors

  • Iftikhar Athar Rasool Department of Dermatology, Mohtarma Shaheed Benazir Bhutto General Hospital, Quetta
  • Shereen Khan Department of Dermatology, Bolan Medical College/ Complex Hospital, Quetta.
  • Khalil Ahmed Bolan Medical College/ Complex Hospital Quetta
  • Nusrat Department of Dermatology, Sandeman (Provincial) Hospital, Quetta
  • Nasruddin Bolan University of Medical and Health Sciences, Quetta
  • Farhan Mir Institute of Skin Diseases Sindh Karachi

Keywords:

Anti HCV antibodies, Lichen planus, Lichen planopilaris, Hepatitis C, Quetta Extrahepatic manifestions, Oral LP

Abstract

Background Lichen planus (LP) is a common inflammatory disorder of the skin and mucous membranes having an unknown etiology. In addition to skin and mucous membranes, it also involves nails and hair. Classically it is characterized by pruritic, purple, polygonal, plan-topped papules and may have different clinical presentations like erosive, hypertrophic, atrophic, follicular (Lichen planopilaris), linear, actinic, pigmentosus, annular, guttate, and vesiculobullous. In recent years, many research articles showed association of Lichen planus with HCV infection. So, it is important to establish the clinical role of Lichen planus in the diagnosing of hepatitis C virus is an a pivotal and practical task.   Methods This is a cross sectional study, having consecutive sampling of Non probability type. It is conducted at department of dermatology, Sandeman (Provincial) Hospital/ Bolan Medical College Quetta between January 2018 to June 2018. All the patients of either gender, aged 30 to 60 years and clinically diagnosed with Lichen Planus were enrolled. After a complete history and clinical examination, anti HCV antibodies was checked by kit method in the institutional laboratory.   Results The mean age was 46.42 ±9.75 years. There were 89 (53.9%) females while 76 (46.1%) males. Mean duration of symptoms was 3.20±1.16 weeks. Frequency of positive anti HCV antibody was found in 53 (32.1%) patients while 112 (67.9%) patients were found to be negative.   Conclusion The results of high frequency of Anti HCV antibodies support a possible association with lichen planus.  

Author Biographies

Shereen Khan, Department of Dermatology, Bolan Medical College/ Complex Hospital, Quetta.

HEAD OF UNIT-2 & ASSISTANT PROFESSOR , DEPARTMENT OF DERMATOLOGY,  BOLAN MEDICAL COMPLEX HOSPITAL / BOLAN UNIVERSITY OF MEDICAL AND HEALTH SCIENCES,  QUETTA,  BALOCHISTAN

Khalil Ahmed, Bolan Medical College/ Complex Hospital Quetta

ASSISTANT PROFESSOR,  MEDICINE UNIT-IV, BOLAN MEDICAL COMPLEX HOSPITAL / BOLAN UNIVERSITY OF MEDICAL AND HEALTH SCIENCES,  QUETTA,  BALOCHISTAN  CO-AUTHOR FOR THIS ARTICLE 

Nasruddin, Bolan University of Medical and Health Sciences, Quetta

RESIDENT DERMATOLOGY,  DEPARTMENT OF DERMATOLOGY, UNIT-1, SANDEMAN (PROVINCIAL) HOSPITAL / BOLAN UNIVERSITY OF MEDICAL AND HEALTH SCIENCES , QUETTA BALOCHISTAN

Farhan Mir, Institute of Skin Diseases Sindh Karachi

CONSULTANT DERMATOLOGIST,  INCHARGE PSORIASIS-VITILIGO CLINIC, INSTITUTE OF SKIN DISEASES SINDH, KARACHI, WWW.ISDSK.COM.PK

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Published

2024-04-21

How to Cite

1.
Rasool IA, Khan S, Ahmed K, Nusrat, Nasruddin, Mir F. Frequency of anti-HCV antibodies in lichen planus patients attending a tertiary care hospital Quetta, Balochistan. J Pak Assoc Dermatol [Internet]. 2024Apr.21 [cited 2024May22];34(2):441-4. Available from: https://jpad.com.pk/index.php/jpad/article/view/2333

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Original Articles