Progressive sarcoma Kaposi after COVID-19

Authors

  • Julia Molochkova
  • Maria Kartashova Moscow Regional Research and Clinical Institute ("MONIKI")
  • Maria Monaenkova Moscow Regional Research and Clinical Institute ("MONIKI")

Keywords:

Sarcoma Kaposi, COVID-19, immunosupression, HHV-8, SARS-CoV-2

Abstract

This article deals with the sarcoma kaposi worsening after severe coronavirus infection.After 2 years of sarcoma Kaposi remission a 70-year-old male HIV-negative patient noted new violaceous skin nodules. A few months before he recovered from COVID-19. We present the case and review of literature.

Author Biographies

Julia Molochkova

Head of dermatology department

Maria Kartashova, Moscow Regional Research and Clinical Institute ("MONIKI")

researcher of dermatology department

Maria Monaenkova, Moscow Regional Research and Clinical Institute ("MONIKI")

junior researcher of dermatology department

References

Cesarman E, Damania B, Krown SE, Martin J, Bower M, Whitby D. Kaposi sarcoma. Nat Rev Dis Primers. 2019;5(1):9. Published 2019 Jan 31. doi:10.1038/s41572-019-0060-9

https://ictv.global/taxonomy/taxondetails?taxnode_id=202101510

Katano H. Pathological Features of Kaposi's Sarcoma-Associated Herpesvirus Infection. Adv Exp Med Biol. 2018;1045:357-376. doi:10.1007/978-981-10-7230-7_16

Sbaraglia M, Bellan E, Dei Tos AP. The 2020 WHO Classification of Soft Tissue Tumours: news and perspectives. Pathologica. 2021;113(2):70-84. doi:10.32074/1591-951X-213

Tembo R, Kaile T, Kafita D, et al. Detection of Human Herpes Virus 8 in Kaposi's sarcoma tissues at the University Teaching Hospital, Lusaka, Zambia. Pan Afr Med J. 2017;27:137. Published 2017 Jun 22. doi:10.11604/pamj.2017.27.137.11845

Pereira PF, Cuzzi T, Galhardo MC. Immunohistochemical detection of the latent nuclear antigen-1 of the human herpesvirus type 8 to differentiate cutaneous epidemic Kaposi sarcoma and its histological simulators. An Bras Dermatol. 2013;88(2):243-246. doi:10.1590/S0365-05962013000200010

Denis D et al. A fifth subtype of Kaposi’s sarcoma, classic Kaposi’s sarcoma in men who have sex with men: a cohort study in Paris. J. Eur. Acad. Dermatol. Venereol. 32, 1377–1384 2018

Mariggiò G, Koch S, Schulz TF. Kaposi sarcoma herpesvirus pathogenesis. Philos Trans R Soc Lond B Biol Sci. 2017;372(1732):20160275. doi:10.1098/rstb.2016.0275

Calabresi A, Ferraresi A, Festa A, et al. Incidence of AIDS-defining cancers and virus-related and non-virus-related non-AIDS-defining cancers among HIV-infected patients compared with the general population in a large health district of Northern Italy, 1999-2009. HIV Med. 2013;14(8):481-490. doi:10.1111/hiv.12034

Semeere AS, Busakhala N, Martin JN. Impact of antiretroviral therapy on the incidence of Kaposi's sarcoma in resource-rich and resource-limited settings. Curr Opin Oncol. 2012;24(5):522-530. doi:10.1097/CCO.0b013e328355e14b

Liu Z, Fang Q, Zuo J, Minhas V, Wood C, Zhang T. The world-wide incidence of Kaposi's sarcoma in the HIV/AIDS era. HIV Med. 2018;19(5):355-364. doi:10.1111/hiv.12584

Robey RC, Bower M. Facing up to the ongoing challenge of Kaposi's sarcoma. Curr Opin Infect Dis. 2015;28(1):31-40. doi:10.1097/QCO.0000000000000122#

Dourmishev LA, Dourmishev AL, Palmeri D, Schwartz RA, Lukac DM. Molecular genetics of Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8) epidemiology and pathogenesis. Microbiol Mol Biol Rev. 2003;67(2):175-212. doi:10.1128/MMBR.67.2.175-212.2003

Grabar S, Costagliola D. Epidemiology of Kaposi's Sarcoma. Cancers (Basel). 2021;13(22):5692. Published 2021 Nov 14. doi:10.3390/cancers13225692

Cahoon EK, Linet MS, Clarke CA, Pawlish KS, Engels EA, Pfeiffer RM. Risk of Kaposi sarcoma after solid organ transplantation in the United States. Int J Cancer. 2018;143(11):2741-2748. doi:10.1002/ijc.31735

Esser S, Schöfer H, Hoffmann C, et al. S1 Guidelines for the Kaposi Sarcoma. J Dtsch Dermatol Ges. 2022;20(6):892-904. doi:10.1111/ddg.14788

Denis D, Seta V, Regnier-Rosencher E, et al. A fifth subtype of Kaposi's sarcoma, classic Kaposi's sarcoma in men who have sex with men: a cohort study in Paris. J Eur Acad Dermatol Venereol. 2018;32(8):1377-1384. doi:10.1111/jdv.14831

Achenbach CJ, Harrington RD, Dhanireddy S, Crane HM, Casper C, Kitahata MM. Paradoxical immune reconstitution inflammatory syndrome in HIV-infected patients treated with combination antiretroviral therapy after AIDS-defining opportunistic infection. Clin Infect Dis. 2012;54(3):424-433. doi:10.1093/cid/cir802

Stallone G, Schena A, Infante B, et al. Sirolimus for Kaposi's sarcoma in renal-transplant recipients. N Engl J Med. 2005;352(13):1317-1323. doi:10.1056/NEJMoa042831

Nichols LA, Adang LA, Kedes DH. Rapamycin blocks production of KSHV/HHV8: insights into the anti-tumor activity of an immunosuppressant drug. PLoS One. 2011;6(1):e14535. Published 2011 Jan 14. doi:10.1371/journal.pone.0014535

FM Buonaguro; ML Tornesello; L Buonaguro; RA Satriano; E Ruocco; G Castello; V Ruocco (2003). Kaposi's sarcoma: aetiopathogenesis, histology and clinical features. , 17(2), 138–154. doi:10.1046/j.1468-3083.2003.00670.x

Koop, H. O., Holodniy, M., & List, A. F. (1987). Fulminant Kaposi’s sarcoma complicating long-term corticosteroid therapy. The American Journal of Medicine, 83(4), 787–789. doi:10.1016/0002-9343(87)90916-8

Hertzler G, Gordon SM, Piratzky J, Henderson JM, Gal AA. Case report: fulminant Kaposi's sarcoma after orthotopic liver transplantation. Am J Med Sci. 1995;309(5):278-281. doi:10.1097/00000441-199530950-00007

Etemad, Shervin A, and Anna K Dewan. “Kaposi Sarcoma Updates.” Dermatologic clinics vol. 37,4 (2019): 505-517. doi:10.1016/j.det.2019.05.008

Lebbe C, Garbe C, Stratigos AJ, et al. Diagnosis and treatment of Kaposi's sarcoma: European consensus-based interdisciplinary guideline (EDF/EADO/EORTC). Eur J Cancer. 2019;114:117-127. doi:10.1016/j.ejca.2018.12.036

Higgins V, Sohaei D, Diamandis EP, Prassas I. COVID-19: from an acute to chronic disease? Potential long-term health consequences. Crit Rev Clin Lab Sci. 2021;58(5):297-310. doi:10.1080/10408363.2020.1860895

Melnikova VO, Dobroff AS, Zigler M, et al. CREB inhibits AP-2alpha expression to regulate the malignant phenotype of melanoma. PLoS One. 2010;5(8):e12452. Published 2010 Aug 27. doi:10.1371/journal.pone.0012452

Daniel P, Filiz G, Brown DV, et al. Selective CREB-dependent cyclin expression mediated by the PI3K and MAPK pathways supports glioma cell proliferation. Oncogenesis. 2014;3(6):e108. Published 2014 Jun 30. doi:10.1038/oncsis.2014.21

Zhou M, Liu X, Li Z, Huang Q, Li F, Li CY. Caspase-3 regulates the migration, invasion and metastasis of colon cancer cells. Int J Cancer. 2018;143(4):921-930. doi:10.1002/ijc.31374

Ebrahimi Sadrabadi A, Bereimipour A, Jalili A, Gholipurmalekabadi M, Farhadihosseinabadi B, Seifalian AM. The risk of pancreatic adenocarcinoma following SARS-CoV family infection. Sci Rep. 2021;11(1):12948. Published 2021 Jun 21. doi:10.1038/s41598-021-92068-4

Alpalhão M, Ferreira JA, Filipe P. Persistent SARS-CoV-2 infection and the risk for cancer. Med Hypotheses. 2020;143:109882. doi:10.1016/j.mehy.2020.109882

Policard M, Jain S, Rego S, Dakshanamurthy S. Immune characterization and profiles of SARS-CoV-2 infected patients reveals potential host therapeutic targets and SARS-CoV-2 oncogenesis mechanism. Virus Res. 2021;301:198464. doi:10.1016/j.virusres.2021.198464

Dursun R, Temiz SA. The clinics of HHV-6 infection in COVID-19 pandemic: Pityriasis rosea and Kawasaki disease. Dermatol Ther. 2020;33(4):e13730. doi:10.1111/dth.13730

Saade A, Moratelli G, Azoulay E, Darmon M. Herpesvirus reactivation during severe COVID-19 and high rate of immune defect. Infect Dis Now. 2021;51(8):676-679. doi:10.1016/j.idnow.2021.07.005

Nasrullah A, Patel S, Ud Din MT, et al. A case of acquired immunodeficiency syndrome-related Kaposi sarcoma in a patient with COVID-19 - A brief review of HIV-COVID Co-infection and its Therapeutic challenges!. Respir Med Case Rep. 2021;34:101524. doi:10.1016/j.rmcr.2021.101524

Gardini G, Odolini S, Moioli G, et al. Disseminated Kaposi sarcoma following COVID-19 in a 61-year-old Albanian immunocompetent man: a case report and review of the literature. Eur J Med Res. 2021;26(1):152. Published 2021 Dec 20. doi:10.1186/s40001-021-00620-9

Magri F, Giordano S, Latini A, Muscianese M. New-onset cutaneous kaposi's sarcoma following SARS-CoV-2 infection. J Cosmet Dermatol. 2021;20(12):3747-3750. doi:10.1111/jocd.1454

Aram K, Patil A, Goldust M, Rajabi F. COVID-19 and exacerbation of dermatological diseases: A review of the available literature. Dermatol Ther. 2021;34(6):e15113. doi:10.1111/dth.15113

Temiz SA, Kutlu Ö. The development of dermatologic diseases in patients recovered from COVID-19. Dermatol Ther. 2021;34(2):e14791. doi:10.1111/dth.14791

Leoni E, Cerati M, Finzi G, Lombardo M, Sessa F. COVID-19 and HHV8 first spotted together: an affair under electron microscopy. J Eur Acad Dermatol Venereol. 2021;35(5):e311-e312. doi:10.1111/jdv.17123

Yanes, Ryan R et al. “Detection of SARS-CoV-2 and HHV-8 from a large pericardial effusion in an HIV-positive patient with COVID-19 and clinically diagnosed Kaposi sarcoma: a case report.” Tropical medicine and health vol. 50,1 72. 24 Sep. 2022, doi:10.1186/s41182-022-00464-x

J, Dai L, Barrett L, et al. SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus. Commun Biol. 2021;4(1):682. Published 2021 Jun 3. doi:10.1038/s42003-021-02220-z

Cohen-Barak, Eran et al. “Kaposi's sarcoma in a patient with pemphigus vulgaris.” International journal of dermatology vol. 55,1 (2016): 85-8. doi:10.1111/ijd.12420

Wang, Tao et al. “Identification of human herpesvirus-8 in Kaposi's sarcoma with bullous pemphigoid.” Chinese medical journal vol. 127,4 (2014): 786-8.

Choi KH, Byun JH, Lee JY, Cho BK, Park HJ. Kaposi sarcoma after corticosteroid therapy for idiopathic thrombocytopenic purpura. Ann Dermatol. 2009;21(3):297-299. doi:10.5021/ad.2009.21.3.297

Simeoni, Sara et al. “Dermatomyositis complicated with Kaposi sarcoma: a case report.” Clinical rheumatology vol. 26,3 (2007): 440-2. doi:10.1007/s10067-005-0148-3

Zerbi S, Saruggia M, Brambilla L, Lodeville D, Buccianti G. Kaposi's sarcoma in a patient with focal glomerulosclerosis. J Nephrol. 2001;14(4):299-303.

L. Zhang, F. Zhu, L. Xie, C. Wang, J. Wang, R. Chen, P. Jia, H.Q. Guan, L. Peng, Y. Chen, P. Peng, P. Zhang, Q. Chu, Q. Shen, Y. Wang, S.Y. Xu, J.P. Zhao, M. Zhou, Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan, China, Annals of Oncology, vol. 31, Iss. 7, 2020, p. 894-901, ISSN 0923-7534, https://doi.org/10.1016/j.annonc.2020.03.296

Downloads

Published

2023-10-12

How to Cite

1.
Molochkova J, Kartashova M, Monaenkova M. Progressive sarcoma Kaposi after COVID-19. J Pak Assoc Dermatol [Internet]. 2023Oct.12 [cited 2023Nov.28];33(4):1685-93. Available from: https://jpad.com.pk/index.php/jpad/article/view/2309

Issue

Section

Case Reports