Ecthyma gangrenosum-like lesions caused by Candida sp.: A review of literature
Keywords:Ecthyma gangrenosum-like lesions, Ecthyma gangrenosum, Candida sp., Disseminated candidiasis, Pseudomonas aeruginosa
AbstractAbstract Background: Ecthyma gangrenosum (EG) is an uncommon, severe, and invasive cutaneous infection typically caused by Pseudomonas aeruginosa. The skin lesion starts off as an erythematous nodule and progresses to a necrotic ulcer with central black eschar. Candida sp. is one of the other species that has been linked to EG-like lesions. Methods: By entering the keywords "Ecthyma gangrenosum" and "Candida" or "Candidal" or "Candidiasis" into PubMed, this review of the literature was conducted. The outcomes were not subjected to any filters or limitations on language. Results: Eight studies and nine cases with EG-like lesions connected to Candida sp. were evaluated and were available on PubMed between 1979 and 2016. One of the nine case reports had neonates as young as 12 days old, while the others in age from 21 to 69. Numerous case reports have used the culture in addition to the biopsies. Pseudohyphae or budding yeast were found in seven out of nine instances of histopathology. Three out of 9 cases reported as disseminated candidiasis. Conclusions: A candida infection, especially disseminated candidiasis, should be included in the differential diagnosis of an immunocompromised patient who shows necrotic lesions that mimic EG and be verified by biopsy as well as culture. Key words: Ecthyma gangrenosum-like lesions, ecthyma gangrenosum, Candida sp., disseminated candidiasis, Pseudomonas aeruginosa
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