Efficacy of intralesional vitamin D3 in cutaneous warts
Keywords:Plantar warts, Cutaneous warts, Intralesional treatment, Vitamin D3, Efficacy
AbstractObjective: The objective of this study was to determine the efficacy of intralesional vitamin D3 in cutaneous warts Study Design: Descriptive Case Series Study Place and Duration of Study: Department of Dermatology, Jinnah Postgraduate Medical Centre, Karachi from August 2018 to February 2019. Methodology: The study comprised 226 patients with palmoplantar warts of various sizes and duration. After injecting lignocaine with 0.2 ml (20 mg/ml), about 0.5 mL of vitamin D3 solution (200,000 IU, 15 mg/mL) was administered to the base of the warts. At 2-week intervals, up to 5 warts might be injected every session until they disappeared, which could take up to 4 treatments. Following the final injection, patients were monitored for 6 months to look for any recurrence. Results: The study was completed by 226 patients. The average number of injections needed to obtain a complete resolution was 2.93+0.60. Complete response was observed in 185 (81.9%) patients. Conclusion: Cutaneous warts can be treated effectively, affordably, and safely with intralesional vitamin D3. Keywords: Plantar Warts, Cutaneous Warts, Intralesional Treatment, Vitamin D3, Efficacy.
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