Comparison of oral fluconazole versus itraconazole for treatment of recurrent oral candidiasis

Authors

  • Zaib DHQ Teaching Hospital/ Sargodha Medical College, University of Sargodha, Sargodha
  • Farwa Naqvi Sargodha Medical College , University of Sargodha, Sargodha
  • Saira Mohsin Zahida Walfare Hospital Lahore
  • Nadeem Yaqoob Niazi Medical and Dental College Sargodha
  • Abdul Mudabbir Rehan D.G. Khan Medical and Dental College, Dera Ghazi Khan
  • Ahmad Amin Khan Fraz Amin Medical Center, Chiniot

Abstract

Objective To compare the efficacy of oral fluconazole versus itraconazole in oral candidiasis.   Methods This study was conducted at the Outpatient Department of Dermatology, DHQ Teaching Hospital, Sargodha Medical College Sargodha. A total of 240 patients were included in this study were divided into two groups containing 120 patients in each group. Both groups applied 2% miconazole gel orally thrice daily for 7-14 days. In addition, group A was prescribed fluconazole 50mg once daily and group B was prescribed itraconazole 100mg twice daily for 7-14 days. Each patient was followed up monthly either physically or on phone for 6 months.   Results In group A, the total number of 45 patients (37.5%) reported back with oral candidiasis whereas 19 patients (15.83%) of group B reported back with oral candidiasis.   Conclusion It is concluded that itraconazole is better than fluconazole for the treatment of recurrent oral candidiasis with a similar duration of treatment.  

Author Biographies

Zaib, DHQ Teaching Hospital/ Sargodha Medical College, University of Sargodha, Sargodha

Department of Dermatology

Saira Mohsin, Zahida Walfare Hospital Lahore

Department of Dermatology

Nadeem Yaqoob, Niazi Medical and Dental College Sargodha

Department of Pharmacology

Abdul Mudabbir Rehan, D.G. Khan Medical and Dental College, Dera Ghazi Khan

Department of Pharmacology

Published

2021-08-06

Issue

Section

Original Articles