Frequency of positive patch tests to nickel in patients suspected of metal contact dermatitis

Authors

  • Amina Afzal
  • Shehla Shaukat
  • Mahwish Zahoor
  • Maryam Rafat
  • Danish Abbas Kazmi
  • Muhammad Nadeem

Keywords:

Allergic contact dermatitis, nickel, patch test

Abstract

Objective To determine the frequency of positive patch tests for nickel in patients suspected of household and occupational metal contact dermatitis.Methods This was a cross-sectional analytical study carried out in the outpatient department of dermatology unit-II, Mayo Hospital, Lahore. A total of 50 patients were inducted in the study with ages 12 and above and either sex, who were suspected of metal contact dermatitis. The patients were patch tested with the allergen nickel sulphate hexahydrate 5% in petrolatum base from the European standard series.Results In this study, out of 50 patients, 62% of the patients positively tested for nickel sulphate out of which 38% of the patients showed a strong positive reaction. Only 12% showed a weak positive reaction whereas 12% patients exhibited an extreme positive reaction. Most patients were females i.e. 46 out of 50. The most commonly affected age group was 21 to 30 years. Most patients belonged to middle class. Housewives and students were most commonly affected. Most frequent symptoms encountered were itching 84%, burning 48%, redness 42% and oozing 36%. The dermatitis aggravated in most patients’ due to hyperhidrosis and wet work.Conclusion Nickel sulphate is a common allergen in patients suspected of metal contact dermatitis. Nickel contact dermatitis is a very common problem prevalent in our community and the cultural trend towards artificial jewelry predisposes our community to risk. 

References

Mark W, David O. Allergic Contact Dermatitis. In: Griffiths C, Creamer D, Barker J, Chalmers R, & Bleeker T.Eds., Rook's Textbook of Dermatology. 9th edn. Oxford: Wiley Blackwell; 2010. P. 128.1-128.81.

Fischer AA. Nickel. The ubiquitous contact allergen. In: Fishers Contact Dermatitis. 5th edn. Philadelphia: Lippincott Williams & Wilkins; 2001. p. 636-49.

Basketter DA, Angelini G, Ingber A, Kern PS, Menné T. Nickel, chromium and cobalt in consumer products: revisiting safe levels in the new millennium. Contact Dermatitis. 2003;49:1-7.

Thyssen JP, Linneberg A, Menné T, Johansen JD. The epidemiology of contact allergens in general population; prevalence and main findings. Contact Dermatitis 2007;57:287-99.

Rycroft RJG, Menne T, Frosch PJ, Lepoittevin JP, eds. Contact Dermatitis 3rd edn. Berlin: Springer; 2001.

Bajaj AK, Saraswat A, Mukhija G, Rastogi S, Yadav S. Patch test experience with 1000 patients. Indian J Dermatol Venereol Leprol. 2007;73:313-38.

Smith MC. Patient education to enhance contact dermatitis evaluation and testing. Dermatol Clin. 2009;27:323-7.

Khan MS. Evaluation and pattern of nickel dermatitis in patients with allergic contact dermatitis (dissertation for fellowship). Karachi: CPSP; 1998. p. 4-5.

Akbar TM. Allergic Hand Eczema: A Clinico Aetiologic Study (dissertation for fellowship). Karachi: CPSP; 1998. P. 73-8.

Castiglioni G, Carosso A, Manzoni S, Nebiolo F, Bugiani M. Results of routine Patch testing of 834 patients in Turin. Contact Dermatitis. 1992;27:182-5.

Groot AC. The frequency of contact allergy in atopic patients with dermatitis. Contact Dermatitis. 1990;22:273-7.

Christophersen J, Menné T, Tanghøj P, Andersen KE, Brandrup F, Kaaber K et al. Clinical Patch Test Data Evaluation by Multivariate Analysis. Contact Dermatitis. 1989;21:291-9.

Koh CK, Walton S. Patch test audit: Are we doing more than we need to? Contact Dermatitis. 1994;31:263-4.

Perrenoud D, Bircher A, Hunziker T, Sutter H, Bruckner‐Tuderman L, Stäger J, et al. Frequency of Sensitization to 13 Common Preservatives in Switzerland. Contact Dermatitis. 1994;30:276-9.

Serra-Baldrich E, Lluch M, Valero A, Malet A, Gimenez CJ. Contact Dermatitis: Clinical Review of 800 Patients Tested Using the Standard European Series. Allergol Immunopathol. 1994;23:67-72.

Leok JT, Goh CL, Ng SK, Wong WK. Changing Trends in Epidemiology in Contact Dermatitis in Singapore. Contact Dermatitis. 1992;26:321-6.

Guillet MH, Wierzbicka E, Guillet S, Dagregorio G, Guillet G. A 3-Year Causative Study of Pompholyx in 120 Patients. Arch Dermatol. 2007;143:1504-8.

Sheretz EF, Swartz SM. Is the Screening Patch Test Tray Still Worth Using? J Am Acad Dermatol. 1993;29:1057-8.

Singh K, Gupta SK, Gupta V, Brar SK. Clinico-epidemiological study on metal-induced contact dermatitis from North India. J Pak Assoc Dermatol. 2015;25:169-76.

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Published

2019-02-17

How to Cite

1.
Afzal A, Shaukat S, Zahoor M, Rafat M, Kazmi DA, Nadeem M. Frequency of positive patch tests to nickel in patients suspected of metal contact dermatitis. J Pak Assoc Dermatol [Internet]. 2019Feb.17 [cited 2024Dec.5];28(4):462-7. Available from: https://jpad.com.pk/index.php/jpad/article/view/1307

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