Autoimmune progesterone dermatitis presented as acute generalized exanthematous pustulosis

Suchibrata Das, Sangita Patra, Saikat Banerjee, Saswati Das

Abstract


Autoimmune progesterone dermatitis (AIPD) is a rare autoimmune response to endogenous progesterone, characterized by cyclic cutaneous and mucosal lesions at the end of the luteal phase with varied type of skin lesions include urticaria, angioedema, erythema multiforme, eczema, folliculitis, papulovesicular eruptions, fixed drug eruption, purpura, or vulvovaginal pruritus and anaphylaxis. We report a case of AIPD presenting as acute generalized exanthematous pustulosis (AGEP). She had papulovesicular lesions with sheet of pustules that appeared in relation with menstrual cycle. Progesterone intradermal test was positive. She was treated successfully with combination oral pills.

 


Keywords


Autoimmune progesterone dermatitis, cyclical, acute generalized exanthematous pustulosis

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References


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