Safety and efficacy of microneedling with autologous platelet-rich plasma in chronic and stable alopecia areata

Nagaratna Chatnallikar, Asha GS, Leelavthy B, Revathi TN


Objective Safety and efficacy of microneedling with autologous platelet-rich plasma (PRP) in chronic and stable alopecia areata.


Methods This study was conducted from September 2013-October 2015 and included 25 patients of alopecia areata attending dermatology OPD of Victoria Hospital and Bowring and Lady Curzon Hospital affiliated to Bangalore Medical College and Research Institute. Patients were included in the study based on the exclusion and inclusion criteria. It was conducted as a randomized prospective study for a period of 12 weeks. SALT score at the baseline and at the end of 12 weeks and hair regrowth at the end of 12 weeks was calculated to see the treatment response.


Results Patients showed statistically significant hair regrowth and decrease in the SALT score from baseline at the end of 12 weeks.


Conclusion Study concluded that microneedling with autologous PRP can serve as a safe and efficient treatment in cases of chronic and extensive alopecia areata for faster hair regrowth.



Alopecia areata, platelet-rich plasma

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Seetharam KA. Alopecia areata: An update. Indian J Dermatol Venereol Leprol 2013;79:563-75.

Safavi KH, Muller SA, Suman VJ, Moshell AN, Melton LJ 3rd.Incidence of alopecia areata in Olmsted County, Minnesota,1975 through 1989. Mayo Clin Proc 1995;70:628-33.

Wasserman D, Guzman-Sanchez DA, Scott K, McMichael A. Alopecia areata. Int J Dermatol 2007;46:121-31

Goh C, Finkel M, Christos PJ, Sinha AA. Profile of 513 patients with alopecia areata: Associations of disease subtypes with atopy, autoimmune disease and positive family history. J Eur Acad Dermatol Venereol 2006;20:1055-60

Messenger AG. Alopecia areata. Disorders of hair. Rook’s text book of dermatology. 9th ed. In: Burns DA, Breathnach SM, Cox NH, Griffiths CE, editors. Oxford,UK: Blackwell publishing limited; 2016. p. 66.31-8.

Dubois M, Baumstarck-Barrau K, Gaudy-Marqueste C, Richard MA, Loundou A, Auquier P, et al. Quality of life in alopecia areata: A study of 60 Cases. J Invest Dermatol 2010;130:2830-3

AlKhalifah A, Alsantali A, Wang E, McElwee KJ, Shapiro J. Alopecia areata update: Part II. Treatment. J Am Acad Dermatol 2010;62:191-202.

Sohn KC, Jang S, Choi DK, Lee YS, Yoon TJ, Jeon EK, et al. Effect of thioredoxin reductase 1 on glucocorticoid receptor activity in human outer root sheath cells. Biochem Biophys Res Commun 2007;356:810-5.

Tan E, Tay YK, Goh CL, Chin Giam Y. The pattern of alopecia areata in Singapore – A study of 219 Asians. Int J Dermatol 2002;41:748-53

Sharma VK,Dawn G,Kumar B. Profile of alopecia areata in northern India.Int J Dermatol 1996:35:22-7

Al-Mutairi N, Eldin ON. Clinical profile and impact on quality of life: Seven years experience with patients of alopecia areata. Indian J Dermatol Venereol Leprol 2011;77:489-93.

Bhat YJ, Manzoor S, Khan AR, Qayoom S. Trace element levels in alopecia areata. Indian J Dermatol Venereol Leprol 2009;75:29-31.

Trink1, E et al* A randomized, double-blind, placebo- and active-controlled, half-head study to evaluate the effects of platelet-rich plasma on alopecia areata. 30 aug 2013 doi:10.1111/bjd.12397.

Sukhbir Singh role of platelet rich plasma in chronic alopecia areata:our centre experience.Indian J Plast Surg. 2015 Jan-Apr; 48(1): 57–59.

Uebel CO, da Silva JB, Cantarelli D, Martins P. The role of platelet plasma growth factors in male pattern baldness surgery. Plast Reconstr Surg 2006; 118:1458–66; discussion 1467.

Suresh H Deepak, Suryanarayan Shwetha. Scalp roller therapy in resistant alopecia areata. J Cutan Aesthet Surg. 2014 Jan-Mar; 7(1): 61–62.


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