Transient acantholytic dermatosis (Grover’s disease) - a case report

Binayak Chandra Dwar Dwari, Arnab Ghosh, Surichhya Bajracharya, Sanjeev Gupta, Nagendra Chaudhar Chaudhary


Transient acantholytic dermatosis was described by Grover. Its definite cause and pathogenesis is unknown. A 22-year-old man presented to our out-patient department with multiple itchy vesicles and pustules on the neck and chest. The biopsy was done and histopathology findings revealed focal acantholytic dyskeratosis. Case was diagnosed as Grover’s disease. Patient was given vitamin A 50000 IU per day and later dapsone was added. Patient was advised to avoid sunlight and heat. This is the first case of biopsy confirmed Grover’s disease fromNepal.



Transient acantholytic dermatosis, Grover’s disease, vitamin A.

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