A case report of chronic sclerosing panniculitis
Keywords:
Sclerosing panniculitis, lipodermatosclerosisAbstract
Sclerosing panniculitis is a fibrotic process that usually occurs on the legs, commonly in women older than 40. The principal features are indurated woody plaques with erythema, edema, telangiectasia, and hyperpigmentation. Although the exact pathogenesis is uncertain, it is thought to occur as a result of ischemic changes.We present a 28-year-old married female who had a 10-year history of painful sclerotic plaques, repeated ulceration and healing with fibrosis of the both lower legs and abdomen. Venogram and Doppler investigations were normal. Skin biopsy from the edge of the ulcer demonstrated the feature of chronic sclerosing panniculitis. Satisfactory improvement was found with methotrexate 7.5mg weekly for 4 months. No recurrence was noted within 1 year follow up.ÂReferences
James WD, Berger TG, Elston DM, eds. Andrews' Diseases of the Skin: Clinical Dermatology. Philadelphia: Saunders/ Elsevier; 2006.
Bruce AJ, Bennett DD, Lohse CM et al. Lipodermatosclerosis: Review of cases evaluated at Mayo Clinic. J Am Acad Dermatol 2002; 46: 187-92.
Ginsburg PM, Ehrenpreis ED, eds. NORD Guide to Rare Disorders. Philadelphia PA: Lippincott Williams & Wilkins; 2003.
Phelps RG, Shoji T. Update on panniculitis. Mt Sinai J Med 2001; 68: 262-7.
Fischer DR, Matthews JB, eds. Sleisenger & Fordtran’s Gastrointestinal and Liver Disease, 7th edn. Philadelphia PA: Saunders Elsevier.; 2002.
Habif TP. Habif: Clinical Dermatology, 4th edn. New York: Mosby; 2004
Luis Requena L, Yus ES, Kutzner H. Panniculitis. In: Wolff K, Goldsmith LA, Katz SI et al., editors. Fitzpatrick’s Dermatology in General Medicine, 7th edn. New York: McGraw-Hill; 2003. P. 569-85.
