Recurrent basal cell carcinoma in patient treated by cryotherapy

Piotr Brzezinski, Jacek Andruszkiewicz, Ahmad Thabit Sinjab, Anca Chiriac


Basal cell carcinoma (BCC) of the skin is the most common malignancy in the human population. One of the most negative features of this disease is frequent tumor recurrence. Unfortunately, all of the traditional diagnostic criteria have failed to definitively predict which patients should be considered at high risk of recurrence. We present an 88-year-old man with recurrent BCC (superficiale multicentricum) occurring three years after successful treatment of BCC (morpheiforme) with cryotherapy. Careful monitoring must be undertaken for at least 3 years; however, the most appropriate course is a lifetime of regular follow-up.



Basal cell carcinoma, cryotherapy, morpheiforme, superficiale

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Asilian A, Momeni I, Khosravani P. Basal cell carcinoma superimposed on a cutaneous leishmaniasis lesion in an immunocompromised patient. J Res Med Sci. 2012;17:108-10.

Lopes Filho LL, Soares Lopes LR, Lima IP et al. [Frontal basal cell carcinoma with superciliar aff ection: surgical treatment with bilateral advancement flap]. Surg Cosm Dermatol. 2009;1:103-4.

Hassan I, Abid K, Mashkoor A, Qazi M. Bazex syndrome – a case report. N Dermatol Online. 2011;2:18-20.

Mahajan VK, Chauhan PS, Mehta KS, Sharma V. Favre-Racouchot Syndrome. Our Dermatol Online. 2013;4:328-9.

Molina AL, Mejía M, Restrepo R. Congenital and multiple basal cell carcinoma. Rev Assoc Colomb Dermatol. 2011;19:85-88.

Toraub K, Jeewon R. Sociodemographic factors and their association to prevalence of skin diseases among adolescents. Our Dermatol Online. 2013;4:281-6.

Hassan I, Dorjay K, Sami A, Anwar P. Sunscreens and antioxidants as photo-protective Measures: An update. Our Dermatol Online. 2013;4:369-74.

Laniauskaite I, Ožalinskaite A, Strupaite R, Bylaite M. Skin cancer knowledge, attitude and behavior towards sun exposure among young adults in Lithuania. Our Dermatol Online. 2011;2:189-95.

Martínez Braga G, Riveros R, Di Martino Ortiz B et al. Dermatoscopy: contribution as a method to define surgical margins in basal cell carcinomas of the face, neck and trunk. Our Dermatol Online. 2013;4:28-31.

Ejaz A, Aurangzeb, Awan ZI, Bux H. Basal cell carcinoma involving the skin of breast ñ a rare site. J Pak Assoc Dermatol. 2006;16:49-51.

Lezcano L, Di Martino Ortiz B, Rodriguez Masi M et al. [Bowen’s disease treated with cryotherapy combined with topical 5% imiquimod. Alternative treatment to surgery in elderly patients with co-morbidities. N Dermatol Online. 2011;2:61-4.

López M, Pasquali P. Management of basal cell carcinoma high riesgo. Dermatol Venezol. 2006;44:388.

Sinjab AT, Brzeziński P. Cryotherapy for Bowen's disease. Own experience. Dermatol Prakt. 2012;4:17-22.

Sinjab AT, Brzeziński P. Cryotherapy as an alternative treatment in keratoacanthoma. Own experience. Dermatol Prakt. 2012;5:31-6.

Al-Bdour M, Al-Khateeb M. Reconstruction of nasal skin defects following excision of basal cell carcinoma. N Dermatol Online. 2011;2:125-9.

Sartore L, Lancerotto L, Salmaso M et al. Facial basal cell carcinoma: analysis of recurrence and follow-up strategies. Oncol Rep. 2011;26:1423-9.

Bartoš V, Pokorný D, Zacharová O et al. Recurrent basal cell carcinoma: a clinicopathological study and evaluation of histomorphological findings in primary and recurrent lesions. Acta Dermatovenerol Alp Panonica Adriat. 2011;20:67-75.

Chiriac A, Mihaila D, Foia L, Solovan C. Basal cell carcinomas in elderly patients treated by cryotherapy. Clin Interv Aging. 2013;8:341-4.

Hamilton JR, Parvataneni R, Stuart SE, Chren MM. Recurrence 5 years after treatment of recurrent cutaneous basal cell and squamous cell carcinoma. JAMA Dermatol. 2013;149:616-8.

Blixt E, Nelsen D, Stratman E. Recurrence rates of aggressive histologic types of basal cell carcinoma after treatment with electrodesiccation and curettage alone. Dermatol Surg. 2013;39:719-25.


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