A Comprehensive Evaluation of Biofillers for Infraorbital Rejuvenation
Keywords:
Undereye Biofillers, platelet-rich plasma, infraorbital rejuvenation, minimally invasive treatment.Abstract
Background: The increased demand of non-surgical cosmetic procedures has led to the popularity of infraorbital rejuvenation with autologous Biofillers because of their minimally invasive and biocompatible nature and cost-effectiveness. Dark circles around the eyes and loss of volume due to aging are relevant to facial aesthetics. Unlike hyaluronic acid fillers, Biofillers, having the origins in platelet-rich plasma (PRP), provide a regenerative and safer choice, as it uses own biological material to enhance the treatment of areas under the eye. Objective: To evaluate the effectiveness of undereye Biofillers for infraorbital rejuvenation and with side effect profile and follow up. Methods: Biofiller treatment was performed in 30 participants, 25-55 years of age who had mild to moderate undereye concerns. Biofiller was obtained by withdrawing blood followed by centrifugation, plasma separation and its heating and cooling to an opaque color before injection. Patients received two injections, 4 weeks apart. Subjective and photographic evaluation of outcomes such as improvement in hollowness, reduction in peri orbital hyperpigmentation and side effects were measured with visual analog scales before treatment, imme-diately after treatment and at 4 weeks and 12 weeks from the treatment. Results: Overall satisfaction and improvement in aesthetic appearance reflected by the mean scores of 8.0 and 7.5 respectively was high. The side effects were not severe and were transient, lasting for a period of 3 to 5 days and a mean pain score noted was 6.5. The data points to the satisfactory to good response with low side effect profile in infraorbital rejuvenation with Biofillers. Conclusion: Biofillers for infraorbital rejuvenation is an economically viable method effectively showing imp-rovement in appearance of under eyes, both in improvement of hollowness and reduction of pigmentation and is accompanied by mild side effects.References
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