The beneficial effect of Aloe vera in skin barrier function improvement: a double-blind randomized trial of Madurese batik craftswomen

Authors

  • Menul Ayu Umborowati, MD Department of Dermatology and Venereology, Faculty of Medicine Universitas Airlangga/ Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
  • Sylvia Anggraeni, MD Department of Dermatology and Venereology, Faculty of Medicine Universitas Airlangga/ Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
  • Damayanti, MD, PhD Department of Dermatology and Venereology, Faculty of Medicine Universitas Airlangga/ Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
  • Prof. Cita Rosita Sigit Prakoeswa, MD, PhD Department of Dermatology and Venereology, Faculty of Medicine Universitas Airlangga/ Dr. Soetomo General Academic Hospital, Surabaya, Indonesia

Abstract

Background Exposure to chemicals in batik process increases the risk of skin barrier disruption in batik craftswomen. Methods This double-blind randomized trial compared standard moisturizer with 2% aloe vera for Madurese batik craftswomen. The cream is applied to the hands and arms twice a day for 4 weeks. Evaluation of the physiological function of the skin on palms was carried out using a Tewameter, Corneometer, and pH meter to assess trans epidermal water loss (TEWL), stratum corneum hydration, and skin acidity (pH). The evaluation conducted before treatment, on 2nd weeks of treatment, and at the end of the treatment. Results In the control group the hydration value of the stratum corneum was significantly increased at the evaluation of the 2nd week (P = 0.045; CI 95%) and the 4th week (P = 0.010; CI 95%). In the experimental group there was a significant decrease in TEWL value at the 2nd week evaluation (P = 0.004; CI 95%), a significant increase in stratum corneum hydration at the 2nd week (P <0.001; CI 95%) and 4th week evaluation (P <0.001; CI 95%), and significant skin pH at 4th week (P = 0.014; CI 95%). Conclusions Aloe vera benefits in improving the physiological function of the skin in Madurese batik craftswomen.

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Published

2022-03-29

How to Cite

1.
Menul Ayu Umborowati, MD, Sylvia Anggraeni, MD, Damayanti, MD, PhD, Prof. Cita Rosita Sigit Prakoeswa, MD, PhD. The beneficial effect of Aloe vera in skin barrier function improvement: a double-blind randomized trial of Madurese batik craftswomen. J Pak Assoc Dermatol [Internet]. 2022Mar.29 [cited 2024May22];32(1):142-7. Available from: http://jpad.com.pk/index.php/jpad/article/view/1828

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