Comparison of mean platelet volume in patients with psoriasis and healthy individuals

Zaheer Ahmad, Shahid Javaid Akhtar, Muhammad Arif Maan, Uzma Khalid, Abid Hussain


Objective To compare mean platelet volume in patients with psoriasis and healthy individuals.


Methodology This case control study was conducted in outpatients department and indoor of department of Dermatology, DHQ Hospital, Faisalabad. The duration of study was six months. Thirty consecutive patients of psoriais, 20 to 60 years of age and thirty age and gender matched healthy individuals were selected. 2cc venous blood sample from each subject was sent to the pathology laboratory of DHQ Hospital. Mean platelet volume (MPV) was measured as a part of blood complete analysis in Medonic M series Haematology analser.


Results MPV was found higher in the patients of psoriasis as compared to the healthy individuals. The mean value of MPV in the case group was 8.24±1.22 fl, whereas in the control group, it was 7.29±0.77 fl (p<0.05).


Conclusion The study demonstrated that mean platelet volume is increased in patients with psoriasis as compared to healthy individuals. Such patients are at an increased risk of cardiovascular complications.


Psoriasis, platelet activation, mean platelet volume, cardiovascular complications

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