Bacteriological profile and antibiotics susceptibility patterns of complicated skin and skin structure infections in tertiary care hospitals, Peshawar

Aiman Waheed, Ali Amar, Irfanullah Afridi, Sadaf Rauf, Dr. Mehran

Abstract


Objective  To identify various isolates causing complicated skin and skin structure infections with their antibiotic susceptibility patterns.

 

Methods A total of 436 samples of pus/ discharge from skin lesions were collected and cultured. Bacterial colonies were identified by using gram stain and biochemical test. Kirby-Bauer disc diffusion technique was followed for testing antibiotics susceptibility patterns.

 

Results The most commonly affected age group observed in the present study was 15-44 years (44.03%). The predominant Gram-positive bacteria was Staphylococcus aureus and gram negative was Escherichia coli. 20 (19.60%) of S. aureus and 22 (40.74%) of Coagulase negative Staphylococci (CONS) were methicillin resistant. Vancomycin was found as most efficient drug followed by Fusidic acid, linezolid, Amikacin chloramphenicol and gentamicin in case of gram positive isolates. Tigecycline was found as most efficient drug as all isolates were found susceptible to it. Incase of gram negative isolates, maximum resistance was shown to cephalosporin, ampicillin, erythromycin and co-trimoxazole while least resistance was recorded against Ticarcillin, Tazobactam-pipiracillin, amikacin and gentamicin.

 

Conclusion Vancomycin, tigecycline, amikacin, gentamicin and fusidic acid showed more efficacy in the present study.

 


Keywords


Bacteriological profile; antibiotics susceptibility; skin infections

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