Treatment of cutaneous leishmaniasis with photodynamic therapy: The first case report from Khyber Pakhthunkhwa (KPK), Swat Pakistan


  • Aakifullah Khan Swat Institute of Nuclear Medicine and Radiotherapy (SINOR), Swat, Pakistan
  • karim khan SINOR Cancer Hospital
  • Ghufran Biradar Swat Institute of Nuclear Medicine and Radiotherapy (SINOR), Swat, Pakistan
  • Moiz Khan Peshawar Medical College, Peshawar KPK, Pakistan


Cutaneous leishmaniasis, photodynamic therapy, pentavalent antimoniate, photosensitizer, methylaminolevulinate


Cutaneous Leishmaniasis (CL), the most common subtype of leishmaniasis, is a vector borne disease transmitted by sand fly. Herein, we report a case of CL being treated  for the first time with photodynamic therapy (PDT) in KPK, Pakistan.  A 55-year-old female patient presented with a single chronic disfiguring ulcerated lesion on the chin. The patient had received pentavalent antimoniate for the last 2 years, with no satisfactory outcome. We treated the patient with methylaminolevulinate based PDT and observed complete response after three sessions of the PDT treatment, each with a light energy dose of 75 J/cm2. The patient has remained disease-free for over 2 years. This study demonstrates the promising role of PDT in the treatment of CL.

Author Biography

karim khan, SINOR Cancer Hospital

SINOR Cancer hospital, working as senior scientist.


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Case Reports