A clinico-pathological study of cutaneous vasculitis in a tertiary hospital of North India

Jaspriya Sandhu, Sunil Kumar Gupta, Bhavna Garg, Neena Sood

Abstract


Objective Cutaneous vasculitis is often seen in dermatological practice. The etiology maybe infections, drugs, connective tissue disease among others. The objective of this study was to study the clinico-pathological features in patients of cutaneous vasculitis who underwent biopsy.

 

Methods In this retrospective study, data of patients diagnosed with Cutaneous Vasculitis who underwent biopsy over a 3-year-period, between January 2016 and December 2018 was taken.

 

Results There were 53 patients, with slight female preponderance [(F=27 (50.9%), M=26 (49.1%). Mean age= 32.15 years]. The most common cutaneous presentation was palpable purpura seen in 36 patients (67.8%).The most common form was Cutaneous small vessel vasculitis (CSVV) seen in 29 patients (54.7%), followed by Urticarial vasculitis (UV) in 13.2%. Prior drug intake (9.4%) appeared to be the most common eliciting factor. Direct immunofluorescence was done in 10 patients, where it was found to be negative..

 

Conclusion The most commonly seen vasculitis were CSVV and UV. An eliciting factor was found in 22.6% of our patients. Among the histopathological features, there was a statistically significant correlation between the presence of endothelial swelling and HSP, and urticarial infiltrate with UV. No association of drug history with tissue eosinophilia was found. DIF was negative in all 10 patients.

 


Keywords


cutaneous vasculitis, clinico-pathological features of vasculitis

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