General paresis of the insane - A rare case report

Seethalakshmi Ganga vellaisamy, Subramania Adityan Murugan

Abstract


General Paresis of the Insane (GPI) is a meningoencephalitis as a result of direct invasion of Treponema pallidum into the cerebrum, typically develops between 15 and 20 years after initial infection. Mr. X is a 50 year old painter referred to Venereology Department from Neurology Department with 3 years history of gradually progressive behavioural disturbances along with disturbances in speech & difficulty in writing. Blood VDRL & CSF VDRL was found to be reactive. A diagnosis of GPI was made and the patient was treated appropriately. He showed remarkable improvement following treatment.

 

 


Keywords


General Paresis of Insane; Crystalline Penicillin; Lumbar puncture;

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References


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