To estimate the frequency of dermatoses in patients undergoing hemdialysis

Manal Afzaal, Safoora Aamir, Mateen Akram, Anum Arshad


Background The skin is an external reflection of many renal pathologies and hence serves as an important tool for the clinician. Mucocutaneous manifestations are commonly observed among patients with chronic kidney disease undergoing hemodialysis.


Objective To estimate the frequency of dermatoses in patients undergoing hemdialysis.


Study design Descriptive study.


Place and duration of study Dialysis Centre, Shaikh Zayed Hospital, Lahore from 01.06.18 to 30.11.18.


Materials and Methods One hundred and seventy seven patients of chronic kidney disease undergoing hemodialysis of both genders irrespective of dialysis duration were observed for various dermatoses.


Results  There were 109 (61.6%) males and 68 (38.4%) females and male to female ratio was 1.6:1. The age of patients ranged from 11-75 years with the mean age being 45.80±14.30 years. One hundred and twenty patients were found to have skin problems. Xerosis was most common (37.9%) followed by pruritus (30.5%) while diffuse hyperpigmentation was seen in 20.3% of patients. Among the nail findings were onychomycosis (2.8%), Beau’s lines (3.4%). Hair changes such as sparse scalp hair and dry lusterless hair were seen in 10.2% and 1.7% of cases respectively. Other cutaneous findings observed were pallor 5.1%, ichthyosis vulgaris 2.3%, cellulitis 0.6%, bullous eruption at site of AV fistula 0.6%, seborrheic dermatitis 0.6%, scabies 1.1%, Schambergs’ disease 0.6%, calcinosis cutis 1.1%, paronychia 1.1%, angular cheilitis 0.6% and keratosis pilaris 0.6%.


Conclusion A broad range of dermatoses occur in patients with chronic kidney disease on hemodialysis. Many of them negatively impact on quality of life. Their early recognition and treatment are essential in reducing morbidity and mortality.



Dermatoses, chronic kidney disease

Full Text:



Asokan S, Narasimhan M, Rajagopalan V. Cutaneous manifestations in chronic renal failure patients on hemodialysis and medical management. International Journal of Research in Dermatology. 2017; 3: 24-32.

Girisha BS, Noronha TM, Menon A. Cutaneous manifestations in patien with end stage renal disease on hemodialysis. International Journal of Contemporary Medical Research 2016; 3: 1386-1388.

Chanda GM, Chintagunta SR, Arakkal G. Dermatological manifestations in chronic renal failure patients with and without hemodialysis. J NTR Univ Health Sci 2017; 6: 8-14.

Deshmukh SP, Sharma YK, Dash K, Chaudhari NC, Deo KS. Clinicoepidemiological study of skin manifestations in patients of chronic renal failure on hemodialysis. Indian Dermatol Online J 2013; 4: 18-21.

Peres LAB, Passarini SR, Kruge L A. Skin lesions in chronic renal dialysis. Brazilian Journal of Nephrology 2014; 36: 42-47.

Banerjee S. Cutanenous manifestation in renal failure patients. Indian J Dermatol Veuercol leprol 2007; 73: 106-8.

Tajbakhsh R, Dehghan M, Azarhoosh R, Haghighi AN, Sadani S, Zadeh SS, Kabootari M, Qorbani M. Mucocutaneous manifestations and nail changes in patients with end-stage renal disease on hemodialysis. Saudi J Kidney Dis Transpl 2013; 24: 36-40.

Udayakumar P, Balasubramainan S, Rama lingam KS, Lakshi MC, Srinivas CR, Mathew AC. Cutaneous manifestatious in patients with chronic renal failure on hemodialysis. Indian J Dermatol Venereal Leprol 2006; 72: 119-25.

Hajheydari Z, Makhlough A. Cutaneous and mucosal manifestations in patients on maintenance hemodialysis. Iran J Kidney Dis. 2008; 2: 86-90.

Charkhchian M, Beheshti A, Zangivand AA. Dermatologica Sinica Nail disorder among patients on maintenance hemodialysis. 2013; 31: 7-10.

Luqman N, Khalid M, Shaheen JA. Cutaneous manifestations of chronic renal failure in Bahawalpur, Pakistan. J Pak Assoc Dermatol. 2012; 22: 219-23.

Singh K, Thakur A, Dhruv K. Incidence of cutaneous manifestation in patients with end stage renal disease. Int J Adv Med 2017; 4: 989-92.

Baghel N, Awasthi S, Kumar SS. Cutaneous manifestations in patients with chronic kidney diseases on haemodialysis. Int J Res Med Sci 2017; 5: 1673-8.

Sultan MM, Mansour HH, Wahby IM, Houdery AS .Cutaneous manifestations in Egyptian patients with chronic renal failure on regular hemodialysis. J Egypt Women Dermatol Soc. 2010; 7: 49-55.

Mirza R, Wahid R, Talat H. Dermatological manifestations in chronic renal failure patients on haemodialysis. JLUMHS. 2012; 11: 24–28.

Pico MR, Lugo-Somolinos A, Sanchez JL, Burgos-Calderon R. Cutaneous alterations in patients with chronic renal failure. Int J Dermatol. 1992; 31: 860–863.

Tercedor J, Lopez Hemandez B, Manuel rodenas J. Nail diseases in haemodialysis patients: case-control study. Br J Dermatol. 2001; 144: 445–446.

Thomas EA, Pawar B, Thomas A. A prospective study of cutaneous abnormalities in patients with chronic kidney disease. Indian J Nephrol. 2012; 22(2):116–120.

Rivet J, Lebbé C, Urena P et al. Cutaneous calcificationin patients with end-stage renal disease: aregulated process associated with in situ osteopontin expression. Arch Dermatol 2006; 142: 900-6.

Specchio F, Carboni I, Chimenti S, Tamburi F, Nistico' S. Cutaneous manifestations in patients with chronic renal failure on hemodialysis. Int J Immunopathol Pharmacol 2014 ; 27: 1-4.


  • There are currently no refbacks.

ISSN: 1560-9014