A comparative study of efficacy & tolerability of 30% salicylic acid versus 20% salicylic acid + 10% mandelic acid peel for acne vulgaris

Mohamed Sidiq, Seethalakshmi Ganga vellaisamy, Kannan Gopalan, Muthusamy Kandasamy

Abstract


Introduction Acne vulgaris mostly affects the face resulting in low self esteem, depression and  social phobia thereby affecting the quality of life. Chemical peeling is still considered a simple procedure, requiring hardly any instrumentation  which is done in day to day  practice to treat acne vulgaris.

 

Objective To compare the efficacy of 30 % salicylic acid peel (SA) versus 20% salicyclic acid peel with 10% mandelic acid peel (SMP) in the treatment of acne vulgaris.

 

Materials and Methods A total of 50 patients were selected and divided into two groups; A (treated with 30% salicylic acid peel) & B (treated with 20% salicyclic acid peel with 10% mandelic acid peel). Data were coded and analyzed.

 

Results Of the 50 participants, 41 completed all four sessions. Among those 41 patients, 23 belonged to group A and 18 belonged to group B. In group A, 51–75 % improvement was noted in 22 (96%) patients and one (4%) had 26-50% improvement. In group B, 51–75 % improvement was noted in 14 (78%) patients, Three (17%) had 26–50 % improvement, one (6%) patient showed less than 25% improvement.

 

Conclusion This study infers that reduction in active acne lesions was much more with 30% salicylic acid peel, whereas postacne melanosis reduced much with the combination peel (SMP). We conclude that both salicylic acid (SA) and Salicylic+Mandelic acid Peel are efficient, well tolerated and reasonably safe procedure that can be used as treatment modality in acne vulgaris.

 

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Keywords


Acne vulgaris, mandelic acid peel, post acne melanosis, salicylic acid peel

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References


Morrone A, Franco G, Valenzano M. Clinical feature of acne vulgaris in 444 patients with ethnic. J Dermatol 2011; 38: 405-8.

Zaenglein AL, Graber EM, Thiboutot DM. Acne Vulgaris and Acneiform Eruptions. In: Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, Wolff K.eds. Fitzpatrick’s Dermatology in General Medicine.8th ed. New York: McGraw-Hill; 2012.

Tan JK. Psychological impact of acne vulgaris: Evaluating the evidence. Skin Ther Lett 2001; 9: 1-3,9.

Kim RH, Armstrong AW. Current state of acne treatment: Highlighting lasers, photodynamic therapy, and chemical peels. Dermatol Online J. 2011; 17(3):2.

Khunger N. Standard guidelines of care for chemical peels. Indian J Dermatol Venerol Leprol. 2008; 74: S5-S12.

6.Garg VK, Sinha S, Sarkar R. Glycolic acid peels versus Salicylic-Mandelic acid peels in active acne vulgaris and post-acne scarring and hyperpigmentation. Dermatol Surg 2009; 35: 59-65.

Levesque A, Hamzavi I, Seite S, Rougier A and Bissonnette R (2011): Randomized trial comparing a chemical peel containing alipophilic hydroxyl acid derivative of salicylic acid with a salicylic acid peel in subjects with comedonal acne. J Cosmet Dermatol 2011; 10: 174-8.

Briden ME: Alpha – hydroxyacid chemical peeling agents: Case studies and rationale for safe and effective use.Cutis 2004; 73: 18-24.

Taylor MB. Summary of Mandelic Acid for the Improvement of Skin Conditions. Cosmetic Dermatol 1999: 26-28.

Davies M, Marks R. Studies on the effect of salicylic acid on normal skin.Br J Dermatol 1976; 95: 187-92.

Tutakne M.A Vaishampayan S.S Acne, Rosacea, and Perioral Dermatitis. In: Valia. R.G, Valia R.A, Siddappa.K, editors. IADVL. 3rd ed. Vol 1. Bhalani; 2008; 27: 836-859.

Lloyd J: The use of microdermaabrasion for acne: a pilot study. Dermatol Surg 2011; 27: 329.

Shishira. R.Jartarkar, Mallikarjun.M, Bugude. Gangadhar, Manjunatha.P. Mandelic acid chemical peel in Acne vulgaris: A boon or a bane? IOSR Journal of Dental and Medical Sciences (IOSR-JDMS).e-ISSN: 2279-0853, p-ISSN: 2279-0861.Volume 14, Issue 5 Ver. VII (May.2015), PP 32-35.

Sadaf Fasih, Asad Bilal Arif. Salicylic Acid Peeling In The Treatment Of Facial Acne Vulgaris. Pak J Physiol 2016; 12(4).

Doaa S. Sayed and Amira A. Abdel-Motaleb. Salicylic Acid Versus Lactic Acid Peeling In Mild And Moderate Acne Vulgaris. AAMJ, Vol.10, N.3, Sep, 2012, Suppl-2.

Lekakh O, Mahoney AM, Novice K, et al. Treatment of acne vulgaris with salicylic acid chemical peel and pulsed dye laser: a split face, rater-blinded, randomized controlled Trial. J Lasers Med Sci. 2015; 6(4): 167-170. doi:10.15171/jlms.2015.13.

Salomone C, Nicklas C, Navarrete-Dechent C, Droppelmann K, Perez-Cotapos ML. Comparitive study of dietary habits between acne patients and a healthy cohort. Indian J Dermatol Venerol Leprol [serial online] 2012 [cited 2013 Sep 24]; 78: 99-101.

Kaimal S, Thappa DM.Diet in dermatology: Revisited. Indian J Dermatol Venerol Leprol 2010; 76: 103-15.

Spencer EH, Ferdowsian HR, Barnard ND. Diet and acne: A review of the evidence. Int J Dermatol 2009; 48: 339-47.

Williams M, Cunliffe WJ. Explanation for premenstrual acne. Lancet 1973; 2: 1055-7.

Stoll S, Shalita AR, Webster GF, Kaplan R, Danesh S, Penstein A. The effect of the menstrual cycle on acne. Jam Acad Dermatol 2001; 45: 957-60.

Khanna VN, Pandhi KR. Relationship of acne with menstrual period. Indian J Dermatol Venereol Leprol 1991; 57: 138-40.

Al.Ameer AM, Al-Akloby OM. Dermographic features and seasonal variations in patient with acne vulgaris in Saudi Arabia: A hospital-based study. Int J Dermatol 2002; 41: 870-1.

Sardana K, Sharma RC, Sarkar R. Seasonal variation in acne vulgaris-myth or reality. J Dermatol 2001; 29: 484-8.

Lee HS, Kim IH: Salicylic acid peels for the treatment of acne vulgaris in Asian patients. Dermatol Surg 2003; 29: 1196–9.

Kessler E, Flanagan K, Chia C. Comparison of α- and β-hydroxyl acid chemical peels in the treatment of mild to moderately severe facial acne. Dermatol Surg 2008; 34: 45–51.

Bari AU, Iqbal Z, Rahman SB. Tolerance and safety of superficial chemical peeling with salicylic acid in various facial dermatoses. Indian J Dermatol Venereol Leprol 2005; 71: 87-90.


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