Adult onset of inflammatory linear verrucous epidermal nevus: truly a rare experience
Keywords:
Linear verrucous, mosaicism, psoriasiform, nevus, adult onsetAbstract
Inflammatory linear verrucous epidermal nevus is an uncommon variant of epidermal nevus, thought to be caused by unknown postzygotic dominant mutation rescued by genetic mosaicism. Clinically, it presents as intensely pruritic, erythematous, psoriasiform and verrucous, papules and plaques following the lines of Blaschko, mostly involving the single leg. It has usually early life onset. However, since its first description, very few cases have been reported which were of adult onset. We have been able to find less than 10 such cases globally. Herein, we report an adult case of ILVEN in a 24‑year‑old male. XMultiCopyPasteTime to upgrade, it’s free!Simply click on the top left of the extension and register to get access to 10 shortcuts. Your email will remain secure, but we might get in touch for your feedback!References
Altman J, Mehregan AH: Inflammatory linear verrucous epidermal nevus, Arch Dermatol 1971; 104:385-389.
Tiwary AK, Mishra DK. A unique porokeratotic variant of inflammatory linear verrucous epidermal nevus. Indian J Paediatr Dermatol 2017; 18: 237-40.
Hamm H, Happle R: Inflammatory linear verrucous epidermal nevus (ILVEN) in a mother and her daughter, Am Med Genet 1986; 24: 685-690.
Behera B, Devi B, Nayak BB, Sahu B, Singh B, Puhan MR. Giant inflammatory linear verrucous epidermal nevus: Successfully treated with full thickness excision and skin grafting. Indian J Dermatol 2013; 58: 461-3.
Khachemoune A, Janjua SA, Guldbakke KK. Inflammatory linear verrucous epidermal nevus: a case report and short review of the literature. Cutis 2006; 78(4): 261-267.
Toribio J, Quinones PA: Inflammatory linear verrucous epidermal nevus, Dermatologica 1975; 150: 65-69.
Hodge SJ, Barr JM, Owen LG: Inflammatory linear verrucous epidermal nevus, Arch Dermatol 1978; 114: 436-438.
De Jong EMGJ, Rulo HFC, Van De Kerkhof PCM: Inflammatory linear verrucous epidermal nevus (ILVEN) versus linear psoriasis. A clinical, histological and immunohistochemical study. ActaDerm Venereol (Stokh) 1991; 71: 343-346.
Goldman K. Don PC: Adult onset of inflammatory linear verrucous epidermal nevus in a mother and her daughter, Dermatology 1994; 189: 170-172.
Kawaguchi H, Takeuchi M, Ono H, Nakajima H. Adult onset of inflammatory linear verrucous epidermal nevus. J Dermatol 1999; 26: 599-602.
Kosann MK. Inflammatory linear verrucous epidermal nevus. Dermatol Online J 2003; 9: 15.
Vukicevic JS, Milobratovic DJ, Milinkovic MV, Bogdanovic Z. Extensive, adulthood inflammatory linear verrucous epidermal nevus associated with mucinous nevus. Indian J Dermatol Venereol Leprol 2011; 77(5): 607-608.