Clinical and bacteriological study of pyoderma with reference to antibiotic susceptibility profile

Dr. Swati G, Dr. Chandan KS, SB Murgesh


Introduction Pyoderma is one of the commonest clinical conditions encountered in a dermatology clinic.  Present study was conducted to know the culture and sensitivity pattern to routinely used antibiotics in a dermatology clinic for the effective management of pyoderma.


Aims and Objectives i) To study the frequency of various pyogenic skin infections. ii) To know the bacterial etiology of pyodermas. iii) To determine the antibiotic susceptibility profile of pyogenic isolates.


Materials and Methods Among the patients attending our out-patient-department from Jan-2016 to June-2016, we recorded 100 cases of pyoderma and screened them for antibiotic susceptibility.


Results Out of 100 cases of pyoderma, 80% were primary pyoderma and 20% were secondary pyoderma. 18 were diabetics and 13 had history of recurrent episodes. Maximum cases were of impetigo (30%), followed by furuncle (20%) and folliculitis (12%). Secondary pyoderma constituted ulcers (5%), infected scabies (4%) and infected contact dermatitis (3%). Single organism was isolated from 90% of cases and multiple organisms in 3% cases. No growth was seen in 7% cases. Staphylococcus aureus was the most prevalent causative agent observed in 63% of cases, of which coagulase positive were 52% and coagulase negative were 11% followed by Streptococcus (15%), Klebsiella (7%), Proteus (4%) and E coli (4%). MRSA was isolated from a single case. Staph aureus was found to be highly sensitive to tetracycline in 89% of cases, doxycycline 80.4%, mupirocin 79%, fusidic acid 78.6%, gentamicin 76.9%, clindamycin 70.2% and erythromycin 67.4% while resistant to penicillin in 73.2% of cases, amoxicillin 70.6%, framycetin 68.4% and ciprofloxacin 44%.


Conclusion Knowledge of causative organism and antibiotic susceptibility pattern in a given locality is essential to give proper antibiotic therapy and avoid resistance to ineffective drug.



Pyoderma, culture and sensitivity, Staph aureus

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