Comparison of efficacy between intralesional bleomycin and cryotherapy in plantar warts

Jaan Muhammad, Naveed Akhtar, Muhammad Khurram Ahmad, Muhammad Irfan Anwar


Objective To compare the efficacy of intralesional bleomycin and cryotherapy in treating plantar warts.


Material and Methods A total of 160 patients (80 in each group) were enrolled, who were randomly divided into 2 groups. Group A was treated with 0.1% intralesional bleomycin and group B was treated with liquid nitrogen with a cotton swab. Follow-up was carried out at 02, 04 and 06 weeks and the final efficacy was calculated at the end of 06 weeks.


Results Out of 160 patients, 32 (40.0%) male and 48 (60.0%) female were enrolled in intralesional bleomycin group; 30(36.5%) male and 50 (62.5%) females were included in cryotherapy group. Mean±SD of age in intralesional bleomycin and cryotherapy was 28.24±4.2 with C.I (27.30-29.17) and 27.56±3.8 with C.I (26.71-28.40) years, respectively. In comparison of both groups 90% efficacy was found in intralesional bleomycin group whereas 72.5% in cryotherapy group and p value was found to be highly significant i.e. (P=0.005).


Conclusion Intralesional bleomycin is more effective than cryotherapy in the treatment plantar warts.



Intralesional, bleomycin, plantar warts, cryotherapy

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