A Clinico-pathological study of lichen planus in a tertiary care hospital in North Karnataka

Pradeep Vittal Bhagwat, Sujatha Patil, Chandramohan Kudligi

Abstract


Objective To document the incidence, various clinical manifestations and its correlation with histopathological findings.

 

Methods A total of 100 lichen planus patients attending outpatients, in the department of dermatology at Karnataka Institute of Medical Sciences Hubballi were included. Detailed history, thorough physical examination, relevant investigations were done.

 

Results Out of all dermatological outpatient, LP constituted 0.47% of the cases.42% belonged to the age group of 26-40 years, with a female to male ratio of 1.08:1. The disease was more common among housewives (47%), in middle (57%) and low (43%) socioeconomic status people. Majority (60%) of the patients presented within 6 months of duration. 96% of the patients had pruritus. Papular LP was commonest type. Only skin was involved in 86%, skin and mucous membrane were involved in 14%. The commonest site was lower limbs (92%) followed by the upper limbs (82%), trunk (42%). Among oral lesions, reticular type was the commonest over buccal mucosa. Koebner phenomenon was observed in 55% of the patients and nail involvement was seen in 6% of the cases. Histopathological changes of cutaneous LP showed hyperkeratosis (88%), hypergranulosis (87%), lymphocytic infiltration in a band like pattern (87%) in majority of the specimens.

 

Conclusion This study emphasizes the need for detailed history, clinical examination, investigations including biopsy in a case of LP as it can present with various clinical morphology and sites of involvement.

 


Keywords


Lichen planus, histopathology

Full Text:

PDF

References


Daoud MS, Pittelkow MR. Lichen Planus. Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, Wolff K, Editors. Fitzpatrick’s Dermatology in General Medicine, 7th edition. New York: McGraw-Hill; 2008. p.296-312.

Sehgal VN, Rege VL. Lichen planus: an appraisal of 147 cases. Indian J Dermatol Venereol. 1974;40:104

Kanwar AJ, De D. Lichen planus in children. Indian J Dermatol Venereol Leprol. 2010;76:366-72.

Piguet V, Breathnach SM, Le Cleach L. Lichen Planus and Lichenoid Disorders. G Griffiths CEM, Barker J, Bleiker T, Chalmers R, Creamer D. Rook’s Textbook of Dermatology, 9th edition. Oxford: Wiley Blackwell; 2016. P. 37.1-37.20.

Boyd AS, Neldner KH. Lichen planus. J Am Dermatol. 1991;25:593-619.

Kachchwa D, Kachchwa V, Kalla G, Gupta LP. A clinicoetiological profile of 375 cases of lichen planus. Indian J Dermatol Venereol Leprol. 1995;61:276-9.

Parihar A, Sharma S, Battacharya SN, Singh UR. A Clinicopathological study of cutaneous lichen planus. J Dermatol Dermatol Surg. 2015;19:21-6.


Refbacks

  • There are currently no refbacks.


ISSN: 1560-9014