Case of bullous pyoderma gangrenosum in a child

Nadia Ali Azfar, Ummara Rafique, Rafia Hafeez, Tariq Rashid

Abstract


Bullous pyoderma gangrenosum is an atypical variety of pyoderma gangrenosum characterized by rapidly evolving vesicles or bullae that later rupture to form ulcers, commonly associated with underlying hematological malignancy. Various therapeutic options are available, including corticosteroids and other immunosuppressive agents. We present an eight-year-old boy having recalcitrant bullous pyoderma gangrenosum treated successfully with thalidomide.

 


Keywords


Bullous pyoderma gangrenosum, corticosteroids, Thalidomide

Full Text:

PDF

References


Bhat RM. Pyoderma gangrenosum:An update. Indian Dermatol Online J. 2012;3: 7-13

Wollina U. Pyoderma gangrenosum – a review. Orphanet J Rare Dis. 2007;2:19

Konopka CL, Padulla GA, Ortiz MP, Beck AK, Bittencourt MR, Dalcin DC. Pyoderma gangrenosum - A review article. J Vasc Bras. 2013;12:25-33.

Gettler S, Rothe M, Grin C, Grant-Kels J. Optimal treatment of pyoderma gangrenosum. Am J Clin Dermatol. 2003;4:597-608.

Wollina U. Clinical management of pyoderma gangrenosum. Am J Clin Dermatol. 2002;3:149-58.

Patel GK, Rhodes JR, Evans B, Holt PJA. Successful treatment of pyoderma gangrenosum with topical 0.5% nicotine cream. J Dermatol Treat. 2004;15:122-5.

Federman GL, Federman DG. Recalcitrant pyoderma gangrenosum treated with thalidomide. Mayo Clin Proc. 2000;75:842-4.

Daniels LH, Callen JP. Mycophenolate mofetil is an effective treatment for peristomal pyodermagangrenosum. Arch Dermatol. 2004;140:1427-9.

Tüzün Y, Maraşoğlu Ö. Pyoderma gangrenosum. J Turk Acad Dermatol. 2007;1 (3):ss71301r.

Peuckmann V, Fisch M, Bruera E. Potential novel uses of thalidomide. Drugs. 2000;60:273-92.

Malkan UY, Gunes G, Eliacik E, Haznedaroglu IC. Treatment of pyoderma gangrenosum with thalidomide in a myelodysplastic syndrome case. Int Med Case Rep J. 2016;9:61-4.

Wolska K, Michalska-Jakubus M, Pucuła J, Chodorowska G, Dzida G, Mosiewicz J. et al. Bullous pyoderma gangrenosum associated with pancytopenia of unknown origin. Postepy Dermatol Allergol. 2014;31:272-6.

Graham JA, Kathryn Kay Hansen KK, Rabinowitz LG, Esterly NB. Pyoderma Gangrenosum in infants and children: Pediatr Dermatol. 1994;11:10-7.


Refbacks

  • There are currently no refbacks.


ISSN: 1560-9014