Correlation between clinical and mycological diagnosis of onychomycosis

Md Anwar Husain, Mohd. Nurul Alam, Yasmin Joarder, Dr. Wahidujjaman, Monalisa Ferdous


Objective To evaluate the correlation between clinical and mycological diagnosis of onychomycosis.


Methods It was a cross-sectional observational study carried out in the Department of Dermatology and Venereology, Ibn Sina Medical College and National Medical College, Dhaka during the period from January 2014 to December 2015. Total 200 samples were included in this study. Clinical diagnosis of onychomycosis was confirmed by KOH smear and fungal culture.


Results A total of 200 clinically diagnosed patients of onychomycosis were included in this study. Out of 200 patients of onychomycosis, total culture positive were 152 (76%). Both KOH and culture positive were 136 (true positive), KOH-ve but culture positive were 16 (false negative), KOH+ve but culture negative were 8 (false positive), both KOH and culture negative were 40 (true negative). Out of 152 culture positive cases, isolated fungi included Trichophyton mentagrophytes 72 (47%), T. rubrum 64 (42%) and Candida spp. 16 (10%).


Conclusion The study concluded that onychomycosis was predominant among the advance age with slight female preponderance. DLSO was the most common clinical type. Fingernail involvement was more common than toenail involvement. Dermatophytes were the common pathogens.



Onychomycosis, Trichophyton mentagrophytes, T. rubrum, Candida, distolateral subungual onychomycosis

Full Text:



Niranjan HP, Priyanka NP. Study of onychomycosis at a tertiary care hospital in South India. J Evol Med Dent Sci. 2012;1:823.

Grover S. Clinico-mycological evaluation of onychomycosis at Bangalore and Jorhat. Indian J Dermatol Venereol Leprol. 2003;69:284-6.

Veer P, Pathwardhan NS, Damle AS. Study of onychomycosis: Prevailing fungi and pattern of infection. Indian J Med Microbiol. 2007;25:53-6.

Malik NA, Raza N, Nasiruddin. Nondermatophyte molds and yeasts as causative agents in onychomycosis. J Pak Assoc Dermatol. 2009;19:74-8.

Ellis DH, Marley JE, Watson AB, Williams TG. Significance of non-dermatophyte molds and yeasts in onychomycosis, Dermatology. 1997;194(Suppl 1):40-2.

Gupta AK, Jain HC, Lynde CW, MacDonald P, Cooper EA, Summberbell RC. Prevalence and epidemiology of onychomycosis in patients visiting physicians offices: A multicentre Canadian Survey of 15000 patients. J Am Acad Dermatol. 2000;43:244-8.

Derby R, Rohal P, Jackson C, Beutler A, Olsen C. Novel treatment of onychomycosis using over-the-counter mentholated ointment: A clinical case series. J Am Board Fam Med. 2011;24:69-74.

Al-Mutairi N, Eassa BI, Al-Rqobah DA. Clinical and mycologic characteristics of onychomycosis in diabetic patients. Acta Dermatovenerologica Croatica. 2010;18(2): 84-91.

Yenisehirli G, Bulut Y, Sezer E, Gunday E. Onychomycosis infections in the middle black sea region, Turkey. Int J Dermatol. 2009;48:956-9.

Drakensjo IT, Chryssanthou E. Epidemiology of dermatophyte infection Stockholm, Sweden; A retrospective study from 2005-2009. Med Mycol. 2011;49:484-8.

Garcia-Doval I, Cabo F, Monteagudo B, Alvarez J, Ginarte M, Rodrıguez-Alvarez MS et al. Clinical diagnosis of toenail onychomycosis is possible in some patients: cross-sectional diagnostic study and development of a diagnostic rule. Br J Dermatol. 2010;163:743-51.

Jesudanam MT, Rao GR, Lakshmi DJ, Kumari GR. Onychomycosis. A significant medical problem. Indian J Dermatol Venereol Leprol. 2002;68:326-9.

Grag A, Venkatesh V, Singh M, Pathak KP, Kaushal GP, Agrawal SK. Onychomycosis in central India: A clinicoetiologic correlation. Int J Dermatol. 2004;43:498-502.

Gelotar P, Vachhani W, Patel B, MaKWana N. The prevalence of fungi in fingernail onychomycosis. J Clin Diag Res. 2012;1-3.

Adhikari L, Gupta AD. Clinico-aetiologic correlates of onychomycosis in Sikkim, Indian J Pathol Microbiol. 2009;52:194-7.

Neupane S, Pokhrel DB, Pokhrel BM. Onychomycosis: A clinicoepidemiological study. Nepal Med Coll J. 2009;11:292-5.

Bokhari MA, Hussain I, Jahnagir M, Haroon TS, Aman S, Khurshid K. Onychomycosis in Lahore, Pakistan. Int J Dermatol. 1999;38:591-5.

Sanjiv A, Shalini M, Charoo H. Etiological agents of onychomycosis from a tertiary care hospital in Central Delhi, India. Indian J Fundament Appl Life Sci. 2011;1(2):11-4.

Sujatha V, Grover S, Dash K, Singh G. A clinical mycological evaluation of onychomycosis. Indian J Dermatol Venereol Leprol. 2000;66:238-40.

Khondker L, Choudhury AM, Shahidullah M, Khan MSI, Ahamed ARS. Clinico-epidemiological profile of onychomycosis attending in a tertiary care hospital. J Bangladesh Coll Physicians Surg. 2012;30:78-84.

Kiraz M. Yegenoglu Y, Erturan Z, Ang O. The epidemiology of onychomycosis in Istanbul, Turkey. Mycoses. 1999;42:323-9.

Lim JT, Chua HC, Goh CL. Dermatophyte and non-dermatophyte onychomycosis in Singapore. Australas J Dermatol. 1992;33:159-63.

Agarwalla A, Agrawal S, Khanal B. Onychomycosis in Eastern Nepal. Nepal Med Coll J. 2006;8:215-9.

Dogra S, Kumar B, Bhansali A, Chakrabarty A. Epidemiology of onychomycosis in patients with diabetes mellitus in India. Int J Dermatol. 2002;41:647-51.


  • There are currently no refbacks.

ISSN: 1560-9014